Executive Director, RWE Platform

The Role

The Executive Director, RWE Platform, is a pivotal role in the Global Real World Evidence organization who leads real world evidence generation for medical outcomes and implementation science associated with the use of specific mRNA products across all therapeutic areas, diseases prevented or treated, and the mRNA platform generally. The evidence generated must be meaningful, valid, and timely to inform patients, healthcare providers, and healthcare/public health/regulatory decision makers seeking optimal health outcomes. The evidence generation space includes but is not limited to point of care trials or prospective studies enabled with digital health technologies, observational clinical studies using linked licensed data and analytics, and engagements with partner networks globally.

The Global Real World Evidence organization has built and/or curated elements of the RWE Platform iteratively and the Executive Director will provide strategic direction for its continued operation and expansion. The role plans and leads the portfolio of medical affairs studies, ensures quality for internal and external study design and implementation, and authoritatively represents the results of these studies to stakeholders. The Executive Director will also drive RWE policy and methods advancement through cross-industry and public-private consortia.

This role leads an interdisciplinary evidence generation staff executing studies aligned with strategic priorities in global medical affairs and integrated evidence generation plans. The Executive Director closely collaborates with global medical affairs leads, country medical directors, franchise and regional integrated evidence teams, and peer leaders in Global Safety Epidemiology, Therapeutic Areas, and Market Access and Health Economics and Outcomes Research.

Heres What Youll Do

The Executive Director RWE Platform is a strategic leader who will lead a team responsible for:

• Shaping study portfolios and individual study questions to align with global medical affairs and integrated evidence generation plan priorities as well as available RWE Platform elements for maximum impact

• Measuring short- and long-term impact of Modernas mRNA platform products on patients and populations to support differentiation and informed choices by regulators, HTAs/NITAGs, payers, professional societies, individual healthcare providers, and patients

• Leading the planning for the design and implementation of real-world evidence studies including but not limited to effectiveness and comparative effectiveness, assessment of subpopulations, changing treatment patterns, implementation science interventions and outcomes, characterization of the sequelae of prevented or treated disease states, and assessment of patient experience with the mRNA platform

• Assessing stakeholder clinical trials to derive maximum learning

• Engaging with Data Science and Digital to ensure that data are deployed efficiently to generate rapid insights

• Communicating scientific findings internally and externally

The Executive Director RWE Platform will:

• Build, mentor, and manage a high performing team in alignment with a Global to Local approach

• Represent the RWE Platform on Medical, Market Access and Commercial cross-functional teams as a senior subject matter expert on internal and external RWE generation

• Oversee team contributions to global medical affairs and integrated evidence plans, integrated program plans, and launch strategies

• Be responsible for review of medical study protocols, statistical analysis plans, study reports, and publications to maintain the high quality and scientific rigor of deliverables

• Develop RWE Platform contributions to publication plans and submissions to clinical and scientific congresses

• Oversee study conduct and drive associated business processes both internally and with external collaborators and vendors to deliver results

• Ensure the RWE Platform study portfolio and insights delivery pivot to address emerging topics/trends/evidence needs from key external stakeholders

• Lead demonstration projects and engagements with cross-industry and public-private consortia advancing RWE policy and methods

• Develop new data sources as well as visualization and communication approaches

• Lead strategies to support the companys communication of evidence in engagements with regulatory authorities, payors, healthcare providers, and patients

Heres What Youll Need (Minimum Qualifications)

• Advanced degree in epidemiology, health economics, pharmaceutical sciences, or related discipline (MS, MPH, PharmD, PhD)

• Experience leading a team engaged in clinical/pharmaco-epidemiology, registry design, clinical trial design and/or real world evidence generation

• Industry, Service Provider, Academic, Clinical, or Regulatory/Payer experience connected to the medical product development lifecycle

• 12+ years of experience in the analysis of real-world data and generation of real-world insights and evidence

Heres What Youll Bring to the Table (Preferred Qualifications)

• Strong oral and written communication skills including data visualization to influence and effectively engage internal and external audiences

• Prior application of guidance, standards and best practices related to epidemiologic design, statistics/causal inference, and evidence based medicine

• Capacity to manage and prioritize a growing and dynamically changing portfolio of activities in a fast-paced environment

• Leadership experiences and capabilities including the ability to inspire respect and trust from others, negotiate, collaborate, guide the development of the team, incorporate awareness of cultural differences, and maintain drive and optimism to capitalize on changing conditions and overcome adversity

• A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

• Highly competitive and inclusive medical, dental and vision coverage options
• Flexible Spending Accounts for medical expenses and dependent care expenses
• Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
• Family care benefits, including subsidized back-up care options and on-demand tutoring
• Free premium access to fitness, nutrition, and mindfulness classes
• Exclusive preferred pricing on Peloton fitness equipment
• Adoption and family-planning benefits
• Dedicated care coordination support for our LGBTQ+ community
• Generous paid time off, including:
  Vacation, sick time and holidays
  Volunteer time to participate within your community
  Discretionary year-end shutdown
  Paid sabbatical after 5 years; every 3 years thereafter
• Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
• 401k match and Financial Planning tools
• Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
• Complimentary concierge service including home services research, travel booking, and entertainment requests
• Free parking or subsidized commuter passes
• Location-specific perks and extras!

About Moderna

In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit www.modernatx.com.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. Were focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Talent Acquisition Partner or contact the Accommodations team at leavesandaccommodations@modernatx.com. (EEO/AAP Employer)

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