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Genomics Translational Research Senior Scientist

Bristol Myers Squibb Company
Redwood City, California
Start date
May 14, 2023

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Job Details

Working with Us
Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more:

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Tumor Microenvironment Thematic Research Center (TME TRC) is focused on developing therapeutic targets at the intersection of tumor, stromal and immune biology within the TME with the goal of enhancing responsiveness to checkpoint blockade and targeted therapies and transforming response and durability rates for cancer patients. Comprising of scientists across multiple disciplines we are responsible for the biology and translational science necessary to support drug development from target identification through to first in human studies.

Position Summary:

We are seeking a highly motivated and experienced individual with genomics expertise to join the TME TRC Translational Research team at Bristol Myers Squibb in Redwood City, CA. As a member of the NGS team, the successful candidate will perform and develop NGS workflow assays to support biomarker identification and target discovery. The successful candidate will be responsible for the development, optimization, and execution of NGS processes including bulk or single cell transcriptomic, genomic, and epigenomic sequencing platforms. As a key contributor to translational research teams, the candidate will apply genomic methods to inform indication prioritization and pharmacodynamic biomarker discovery and develop prototype biomarker assays for implementation in clinical trials.

Position Responsibilities:
In the role as a Senior Scientist within the TME TRC Translational Research team, the ideal candidate:

  • Accountable for design of hypothesis-driven studies using genomic technologies to inform pharmacodynamics, mechanism of action, and patient stratification/selection.

  • Develops, validates, and applies NGS methods for various genomic, epigenomic and transcriptomic sequencing platforms.

  • Independently plans and executes routine genomic assays. Independently analyzes data, troubleshoots, and determines next steps, and communicates results and timelines to project teams.

  • Draft SOW and manage CRO-based genomic studies to ensure the timely completion of outsourced activities.

  • Partner closely with translational biomarker, bioinformatics, and discovery biology scientists to drive the advancement of therapeutic candidates.

  • Play a key role in providing the relevant translational input to discovery and translational projects as part of interdisciplinary teams.

Experience =

Basic Qualifications:

  • Bachelors Degree

  • 7+ years of academic and / or industry experience


  • Masters Degree

  • 5+ years of academic and / or industry experience


  • Ph.D. or equivalent advanced degree in the Life Sciences

  • 2+ of academic and / or industry experience

Preferred Qualifications:

  • Strongly prefer PhD with either 2+ years of significant biopharmaceutical industry experience or postdoc in genomics field, or MS with 8+ years of relevant experience in genomics research in biopharmaceutical industry.

  • Requires extensive experience performing genomic assays including DNA/RNA preparation, qPCR, ddPCR, NGS library preparation, sequencing and analysis.

  • Previous experience in cancer biology or immuno-oncology with translational research experience highly preferred.

  • Familiarity with biomarker assay development (tumor tissue-based and peripheral genomics and transcriptomics) to guide experimental prioritization is preferred.

  • Proven track record of handling multiple high priority tasks in parallel with internal and external collaborators including CROs and academics.

  • Excellent verbal and written communication skills across all levels both within an organization and with external collaborators/companies with the ability to recognize, articulate, and accept calculated risks to make informed decisions.

  • Comfortable working in a collaborative manner in a fast-paced environment.

  • Willing to work as a topic expert, outside of a traditional functional environment, in a team unified around serving the assets.

The starting compensation for this job is a range from $109,000.00$150,700.00, plus incentive cash and stock opportunities (based on eligibility).

The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience.

For more on benefits, please visit our BMS Careers site.

Eligibility for specific benefits listed in our careers site may vary based on the job and location.




If you come across a role that intrigues you but doesnt perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as Transforming patients lives through science , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to Visit to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.


Bristol Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.

At Bristol Myers Squibb, we believe in the power of science to address some of the most challenging diseases of our time. Our focus on these unmet needs comes during a remarkable time, when unprecedented scientific breakthroughs are advancing the treatment of disease as never before in human history.

We work every day to transform patients’ lives through science. Each day, our employees around the world work together for patients – they are at the center of everything we do. They inspire us. They are the reason we come to work each day.

We combine the agility of a biotech with the reach and resources of an established pharmaceutical company to create a global leading biopharma company powered by talented individuals who drive scientific innovation.

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