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Associate Scientist, Sequencing Specialist, CGR

Employer
Frederick National Laboratory for Cancer Research
Location
Rockville, MD
Start date
May 10, 2023

View more

Discipline
Clinical, Clinical Medicine, Science/R&D, Biotechnology
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
BioCapital

Job Details

Associate Scientist, Sequencing Specialist, CGR

Job ID: req3532
Employee Type: exempt full-time
Division: Clinical Research Program
Facility: Rockville: 9615 MedCtrDr
Location: 9615 Medical Center Drive, Rockville, MD 20850 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.  The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.

PROGRAM DESCRIPTION
 

The Cancer Genomics Research Laboratory (CGR) investigates the contribution of germline and somatic genetic variation to cancer susceptibility and outcomes in support of the NCI's Division of Cancer Epidemiology and Genetics (DCEG), the world’s most comprehensive cancer epidemiology research group. 

CGR is located at the NCI-Shady Grove campus in Rockville, MD and operated by Leidos Biomedical Research, Inc.  We care deeply about discovering the genetic and environmental determinants of cancer, and new approaches to cancer prevention, through our contributions to the molecular, genetic, and epidemiologic research of the 70+ investigators in DCEG.  Working in concert with epidemiologists, biostatisticians and basic research scientists in DCEG’s intramural research program, CGR provides the capacity to conduct genome-wide discovery studies and targeted regional approaches to identify the heritable determinants of various forms of cancer.

This includes the design and analysis of high throughput studies using various types of “–omics” technologies such as array- and sequence-based genome-wide association studies, studies of tumor characteristics using integrated genomic data analysis, and molecular epidemiologic studies based on novel assays focused on the metabolome and microbiome.

We are seeking a highly motivated, independent scientist to join our team to establish and support new sequencing applications for the benefit of DCEG investigators in areas of functional, single cell, and spatial biology.

KEY ROLES/RESPONSIBILITIES

Within CGR, the Genomics Laboratory is a fast-paced, high throughput genotyping and sequencing facility dedicated to the support of genetic and epidemiologic studies for investigators at the National Cancer Institute. We are recruiting for an Associate Scientist position within the Genomics Laboratory to work across our team and in close coordination with other CGR groups and DCEG investigators. The successful candidate will have responsibility for planning, executing, and analyzing a wide range of projects across multiple areas of interest. Key responsibilities include:

  • Utilize molecular biology expertise and available literature to design experimental plans for novel research questions
  • Stay up to date with technological advancements in Next-Generation Sequencing and genomic/multiomic applications
  • With DCEG and CGR senior staff, evaluate, suggest, and implement new technologies to support Division’s research needs
  • Work with DCEG investigators to develop and execute experimental plans in the lab, evaluate and interpret results, and determine follow up actions with minimal supervision
  • Advise researchers on selection and application of genomics and/or proteomics technologies
  • Work seamlessly and collaboratively with multiple teams across CGR including molecular/digital pathology, project management, technology development/optimization, quality management and bioinformatics, utilizing available resources to successfully move projects forward or help integrate new approaches into routine use.
  • Ensure thorough documentation of experimental plans and actions taken

BASIC QUALIFICATIONS

 To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

  • Possession of a Bachelor’s degree from an accredited college or university according to the Council for Higher Education Accreditation
  • A minimum of eight (8) years related biomedical experience
  • Must be able to obtain and maintain a clearance
  • Substantial experience with NGS technologies, techniques, and assay development, including multiple platforms (Illumina, PacBio, Ion Torrent preferred)
  • Experience evaluating and interpreting data generated from NGS experiments
  • Basic understanding of bioinformatic workflows for NGS data
  • Excellent laboratory skills and in-depth knowledge of molecular biology, ability to troubleshoot with minimal supervision
  • Proven experience with implementation of new protocols, including benchmarking different chemistries
  • Ability to maintain currency in fast-moving field of new sequencing applications, chemistries, instrumentation
  • Careful attention to detail
  • Ability to identify critical variables in an experiment
  • Strong organizational skills with the ability to multitask
  • Experience with prioritization in a high-pressure environment
  • Demonstrated ability to deliver highly complex scientific information to a broad range of researchers and technical staff
  • Working knowledge of Windows-based computer operating systems and Microsoft office suite

PREFERRED QUALIFICATIONS

Candidates with these desired skills will be given preferential consideration:

  • Expertise with a wide range of specimens and analytes used in genomics, including DNA, RNA (derived from FFPE)
  • Extensive knowledge and experience of modern molecular biology and/or chemistry tools, including single-cell and spatial biology methods
  • Experience using automated high-throughput laboratory equipment, including liquid handling robotics (use, maintenance, method development)
  • Proven independence and a high degree of flexibility required for a rapidly changing research and technological environment
  • Ability to train and mentor staff

JOB HAZZARDS

  • This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations.
  •  This position may require continuous or intermittent exposure to and exertion in environmental conditions such as working outdoors, temperature extremes, humidity extremes. etc. as part of the job.

Commitment to Diversity
All qualified applicants will receive consideration for employment without regard to sex, race, ethnicity, age, national origin, citizenship, religion, physical or mental disability, medical condition, genetic information, pregnancy, family structure, marital status, ancestry, domestic partner status, sexual orientation, gender identity or expression, veteran or military status, or any other basis prohibited by law. Leidos will also consider for employment qualified applicants with criminal histories consistent with relevant laws.

#readytowork

Company

A rewarding career with global impact

Whether you’re an expert in your field or just starting out, we have a career opportunity for you. We’re always looking for people to join us in fulfilling the mission of the Frederick National Laboratory: discovery, innovation, and success in the biomedical sciences.

Our team of 2,400+ scientists, technicians, administrators, and support staff work at the forefront of basic, translational, and preclinical science, with a focus on cancer, AIDS, and other infectious diseases.

We collaborate with colleagues across the National Cancer Institute, National Institutes of Allergy and Infectious Diseases, and others throughout the National Institutes of Health. We also engage with extramural investigators in academia, government and industry.

Your path to joining our team begins with the desire to work for the only national laboratory dedicated to biomedical research. Our employees share a common desire to help make a difference in cancer research and public health concerns. As you search for a career that fits your education, skills, and abilities, explore the core values that guide us and emphasize work-life balance.

Discover why joining the Frederick National Laboratory team could be the most important career step you take

 

 

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Company info
Website
Phone
301-846-1000
Location
8560 Progress Drive
Frederick
MD
21701
US

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