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Scientific Director - Project Toxicologist (US-REMOTE)

Los Angeles, CA
Start date
May 9, 2023

View more

Science/R&D, Toxicology
Required Education
Bachelors Degree
Position Type
Full time
Biotech Beach, Best Places to Work

Job Details


If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborators who achieve togetherresearching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. Its time for a career you can be proud of.

Scientific Director - Project ToxicologistLive

What you will do

Lets do this. Lets change the world. In this vital role, you will be the key scientific interface between Translational Safety & Bioanalytical Sciences (TS&BA) and your project teams from discovery through post-marketing.

The TS&BA function at Amgen is seeking a Scientific Director to serve as a Project Team Representative (PTR) and a Subject Matter Expert (SME), reporting to the Executive Director US Head Translational Safety and Bioanalytical Sciences Portfolio Scientific Leadership.

You will develop and implement fit-for-purpose nonclinical safety strategies based on a strong scientific foundation, flexibly evolve the strategy in response to team goals and emerging data and lead or influence multidisciplinary teams. As TS&BA PTR, you will partner with Project Teams developing therapeutics using multiple modalities (including biotherapeutics, small molecules and RNA therapies) to treat diseases in inflammation, cardiometabolic diseases, and/or oncology. TS&BA PTRs are encouraged to develop subject matter expertise related to a specific therapeutic area (e.g., obesity, dyslipidemia, etc.), modality, or safety concern. As an SME, you will provide advice, mentorship and support including at relevant occurrences of the TS&BA Portfolio Scientific Advisory Committee.

The successful candidate will have:
  • A sustained track record of scientific leadership as well as in preclinical development with a strong understanding of cross-functional needs and the ability to develop integrated plans to enable successful development of a therapeutic.
  • Organizational management and leadership experience including leadership of multi-disciplinary teams, leadership of critical initiatives and managing through organizational change.
  • Deep expertise in stages of development preceding First-in-Human with a passion for biological understanding and application of biological insights to program success.
  • Experience developing therapeutics of various modalities, e.g., small and large molecules, including fit-for-purpose study designs and selection of nonclinical species.
  • Working knowledge of GLP regulation and regulatory guidelines.
  • Prior work experience at, or collaborating with, contract research organizations.
  • Interest and ability to serve as a Subject Matter Expert in a specific area.
  • Excellent and professional verbal and written communication skills; proven ability to influence a broad spectrum of partners toward achieving business goals.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

Doctorate degree and 4 years of Toxicology, Pharmacology or other related field.


Masters degree and 7 years of Toxicology, Pharmacology or other related field.


Bachelors degree and 9 years of Toxicology, Pharmacology or other related field.

Preferred Qualifications:
  • 10 years of drug development experience including interactions with regulatory agencies.
  • Prior experience with discovery and development of therapeutics for the treatment of cardiometabolic disorders (e.g., obesity).

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being.

The annual base salary range for this opportunity in the U.S. is $187,090 - $214,547. In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans and bi-annual company-wide shutdowns
  • Flexible work models, including remote work arrangements, where possible
Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.
Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancers, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.


We are all different, yet we have this in common: our mission to serve patients. This sense of shared purpose is key to our becoming one of the world’s leading biotechnology companies. It guides us as we continue to launch new medicines and reach millions of patients worldwide.

We live the mission.

We win together.

We thrive on continual challenge.

Our team of 22,000+ scientists and professionals worldwide bring distinct perspectives and experiences to all we do. We leverage our global talent to achieve together—to research, manufacture and deliver ever-better products and greater depth to our mission.

At Amgen, there is a strong correlation between our high level of diversity and performance. Because addressing issues with a wider range of perspectives and approaches leads to more creative problem-solving. Together, we’re transforming the promise of science and biotechnology into therapies that have the power to restore health.

Connect with us to explore how you can Win, Live, and Thrive at Amgen.


Find Us
Corporate Headquarters
One Amgen Center Drive
Thousand Oaks

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