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Senior Scientist, I - Cell Culture Process Development

Worcester, Massachusetts
Start date
May 5, 2023

Job Details

A Senior Scientist position is available within the Cell Culture Process Development group in S&T Biologics at AbbVie Bioresearch Center in Worcester, MA. The group is responsible for developing and supporting cell culture manufacturing processes for early and late phase clinical programs. We strive for speedy delivery of quality processes that are high yield, amenable to efficient manufacturing operations, robust and provide desirable product quality attributes. The group interacts closely with other development groups, along with Manufacturing and Discovery. The selected candidate will be involved in process development, process characterization, tech transfer and scale-up. The candidate will have a major role in aspects of cell culture media development and process optimization. We are seeking an enthusiastic, creative scientist that can work independently and as part of a dynamic team environment.


  • Drive development of methods to characterize cellular metabolic fluxes, application of statistical design and data analysis and generation of models.
  • Work collaboratively and cross-functionally with colleagues in other functional areas (Analytical Development, Cell Line Development, Discovery, Manufacturing and Quality). Develop and characterize highly-productive CHO cell culture processes suitable for cGMP biotherapeutic manufacturing within project timelines, performing technical transfer and manufacturing support activities.
  • Conceive, investigate and execute scientific research and development to significantly improve platform processes and workflows, develop new methods, build technical expertise and intellectual property, and deepen scientific understanding.
  • Maintain a high level of productivity in the lab, with clear and accurate documentation.
  • Serve as a mentor to junior scientists.
  • Proactively seek out new information and opportunities to advance our technologies and pipeline.  Critically evaluate relevant scientific, regulatory and business advances and integrate this knowledge.
  • Effectively communicate scientific data and concepts to internal and external audiences through reports, presentations and manuscripts. Author and review technical reports, protocols, and other key documents.
  • Understand and adhere to corporate standards regarding code of conduct, safety, documentation and GMP compliance.

  • PhD in biochemical/chemical engineering or life sciences related disciplines; or M.S. in biochemical/chemical engineering or life sciences related disciplines with 5+ years of industrial experience
  • Excellent interpersonal and communication skills. Strong scientific curiosity with a passion for problem-solving and optimization. Self-motivated with excellent attention to detail and ability to multi-task. Strong organizational, planning and trouble-shooting skills.
  • Understanding of cell culture processes (e.g., cell and molecular biology, process development, process scale up and scale down, recombinant protein production, protein characterization).
  • Proven experience working aseptically in cell culture processes.
  • Strong interest in cellular metabolism, omics applications and media development.
  • Experience with statistical data analysis tools such as design of experiment and multivariate data analysis preferred.

AbbVie is an equal opportunity employer including disability/vets. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a disabled veteran, recently separated veteran, Armed Forces service medal veteran or active duty wartime or campaign badge veteran or a person’s relationship or association with a protected veteran, including spouses and other family members, or any other protected group status. We will take affirmative action to employ and advance in employment qualified minorities, women, individuals with a disability, disabled veterans, recently separated veterans, Armed Forces service medal veterans or active-duty wartime or campaign badge veterans. The Affirmative Action Plan is available for viewing in the Human Resources office during regular business hours.


AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on Twitter, Facebook, Instagram, and YouTube.

Stock Symbol: ABBV

Stock Exchange: NYSE

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1 North Waukegan Road
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