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Associate Director, Immune Oncology, Precision (Translational) Medicine

Employer
AbbVie
Location
South San Francisco, California
Start date
Apr 22, 2023

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Discipline
Science/R&D, Oncology
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Bay, Best Places to Work

Job Details

We are seeking a highly motivated individual with a proven track record of scientific accomplishments to join our growing Precision Medicine Immune Oncology (IO) organization at AbbVie. As a Biomarker Leader, he/she will have the opportunity to work in a fast-paced and highly collaborative environment to lead the development and execution of Precision Medicine strategies for Oncology programs in early/late-stage clinical development. The successful candidate will lead a cross-functional Precision Medicine Team responsible for development and execution of translational research and clinical biomarker strategies (predictive/pharmacodynamic/resistance biomarkers, molecular response endpoints, indication selection and combination strategies) in alignment with the overall asset strategy, and ensuring successful execution of drug-diagnostic co-development in collaboration with the Companion Diagnostics group within Precision Medicine. This role requires an exceptional translational scientist with outstanding communication and leadership skills to drive effective decisions with key cross-functional stakeholders and enable execution of the overall Precision Medicine strategy for the program.

Responsibilities:

  • Lead the design, development, and execution of the overall Precision Medicine strategy for one or more AbbVie IO programs
  • Design and implement hypothesis-driven strategies to deliver evidence of target engagement, mechanisms of action/resistance, patient selection/CDx strategies (in partnership with CDx Lead), and other clinically relevant biomarker endpoints to advance the AbbVie Oncology pipeline
  • Enable cross functional collaboration on the Precision Medicine strategy, leading the design, execution, analysis, communication, and publication of translational research and correlative clinical biomarker studies
  • Author and review Precision Medicine related sections in clinical study / regulatory documents (i.e. INDs, IBs, trial protocols/ops manuals, ICFs, IRB responses, HA Briefing Books, CSRs, etc)
  • Ensure that overall budget, schedule, and performance standards are attained, and be accountable for the overall Precision Medicine strategy in oncology clinical studies, in compliance with AbbVie’s processes and regulatory requirements
  • Provide oversight of external collaborations (academic/industry/consortia) that advance the overall Precision Medicine objectives for the program
  • Prepare and present Precision Medicine deliverables to governance bodies, review forums, decision committees and project teams
  • Represent Precision Medicine function at advisory boards and health authority interactions to advance translational research and clinical biomarker objectives for the program
  • Drive scientific and/or technical innovation collaboratively with other members of Precision Medicine Oncology

Qualifications:
•    PhD degree in a relevant scientific field (e.g., immunology, oncology, molecular oncology, cancer genetics) with 8+ years of relevant experience in the pharmaceutical industry or equivalent; Master’s Science Degree or PharmD with 14 years of related work; Bachelor’s Degree in Science related field with 16 years of related work experience 
•    Strong scientific background in tumor biology and/or immuno-oncology supported by publication record in these areas. 
•    Demonstrated leadership in development and execution of translational research and clinical biomarker strategies (i.e. predictive/pharmacodynamic/resistance biomarkers, molecular response endpoints, indication selection and combination strategies) in oncology 
•    Experience leading cross-functional teams responsible for developing/implementing Precision Medicine strategies for oncology programs in a drug development setting 
•    Knowledge of clinical trial methodology, regulatory requirements governing clinical trials, companion diagnostics, protocol design, and/or experience in clinical development strategy preferred 
•    Strong passion to drive clinical innovation through Precision Medicine to improve outcomes for patients with cancer 
•    Excellent written and oral communication skills, strong organizational skills with attention to detail, and effective time management with an ability to distill complex issues and clearly articulate/present solutions 
•    Strong interpersonal and collaboration skills to work in a team-oriented, matrix environment, and the ability to interface with multiple cross-functional stakeholders 
 

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.

We offer a comprehensive package of benefits including paid time off. (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees  

This job is eligible to participate in our short-term incentive programs. 

This job is eligible to participate in our long-term incentive programs. 

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is an equal opportunity employer including disability/vets. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a disabled veteran, recently separated veteran, Armed Forces service medal veteran or active duty wartime or campaign badge veteran or a person’s relationship or association with a protected veteran, including spouses and other family members, or any other protected group status. We will take affirmative action to employ and advance in employment qualified minorities, women, individuals with a disability, disabled veterans, recently separated veterans, Armed Forces service medal veterans or active-duty wartime or campaign badge veterans. The Affirmative Action Plan is available for viewing in the Human Resources office during regular business hours.


Company

AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, and YouTube.

Stock Symbol: ABBV

Stock Exchange: NYSE

Company info
Website
Phone
1-800-255-5162
Location
1 North Waukegan Road
North Chicago
Illinois
60064
US

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