Postdoctoral Research Scientist - Biotechnology Discovery Research

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Biotechnology Discovery Research (BioTDR) organization at Lilly discovers best in class and first in class biotherapeutics by integrating biology, chemistry, and innovative scientific capabilities. We are pursuing novel biotherapeutic discovery and targeted delivery of various modalities of drug candidates to specific cells and tissues. To accomplish this, we collaborate with colleagues in both the discovery and development organizations, including scientists in Neuroscience, Immunology, Diabetes and Complications, Oncology, ADME, Toxicology and clinical development. Our main goal is to advance the discovery of breakthrough medicines across a wide range of disease areas. Are you looking for a dynamic research environment and an industry-leading biotechnology group that has a track record of success developing drugs impacting patients’ lives?

We are seeking a curious postdoctoral scientist with a strong background in biology and biochemistry.  We are looking for a problem-solver with experience in building biomolecules and biological model systems in the targeted drug delivery space. The successful candidate will be working collaboratively with subject matter experts to build rational design strategies for targeted delivery of molecules, develop new cell-based assays, and pioneer new strategies for cell-specific delivery.  The candidate will develop and implement in vitro and analytical model systems to enable SAR and testing applications for protein design, nucleic acid delivery, with the goal of advancing new protein designs and targeted molecules.

Specifically, you will have an opportunity to:

• Collaborate closely with computational scientists, protein chemists and biologists to spearhead new systems for targeted delivery of nucleic acids

• Generate impactful data focused on achieving and improving productive oligonucleotide delivery, resulting in selection of specific molecules for further exploration of biology in cells and in in vivo models.

• Contribute to the advancement of novel approaches to evaluate proteins and molecules for their ability to delivery oligonucleotide cargo to cell types of interest, such as neurons, immune cells, adipocytes, pancreatic beta cells and others.

• Surround yourself with multi-disciplinary experts in a highly collaborative, fast paced environment with the opportunity to lead and mentor a team of scientists and research associates.

• Present findings at conferences and publish in high quality peer-reviewed journals.

This position will be embedded in BioTDR's Biotherapeutic Enabling Biology team of Lilly’s Medicines Innovation Hub (MIH), which serves as a groundbreaking scientific center working across all disease areas to identify and develop quality targets, hits, leads, and clinical drug candidates. Apply today and join our team of exceptional employees striving to make an impact in the lives of patients around the world!

Basic Qualifications

• PhD in life sciences related field such as cell biology, molecular biology, bioengineering, biochemistry, pharmacology.

Additional Skills/Preferences

• Direct, hands-on research experience in chemical biology, molecule engineering, and cellular assays.

• Multidisciplinary scientist with technical experience related to in cell culture, cell assays, gene and protein expression analysis, and analytical skills. Experience working with cells and proteins is highly desirable. 

• Ability to work independently and deliver progress in a multi-disciplinary, cross-functional team setting.

• Creative thinker and innovative problem solver with the ability to integrate and apply diverse pieces of information to projects

• Leadership demonstrated through the ability to deliver impactful data to advance projects.

• Excellent written and verbal communication skills.

• Proficiency with advanced scientific software (e.g., Spotfire, JMP, MOE).

Additional Information

• Location: Indianapolis, IN

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law). 

#WeAreLilly