Director-Gene Delivery and Editing; Manufacturing Science and Technology
- Bristol Myers Squibb Company
- Seattle, Washington
- Start date
- Mar 29, 2023
- Clinical, Manufacturing & Production, Science/R&D, Genetics
- Required Education
- Bachelors Degree
- Position Type
- Full time
- Best Places to Work
Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-usPosition: Director - Gene Deliver and Editing; Manufacturing Science and TechnologyLocation: Summit, New Jersey / Seattle, Washington
At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
Come, join the BMS Cell Therapy Operations (CTO) Division, and be a part of the team building leading cell therapy platforms to serve our patients with novel cellular immunotherapies. The Global Manufacturing Science and Technology (GMS&T) Division of CTO plays a critical role in technology transfers, process validation, CMC life cycle management, technical oversight of external manufacturing partners, process engineering and establishing manufacturing standards to enable a robust and scalable global cell therapy manufacturing network.
We are looking for a Director of Manufacturing Technology Support (MTS) to join our Gene Delivery and Editing MS&T (GDE-MS&T) group in GMS&T.
The successful candidate will lead efforts related to vector manufacturing technologies from process performance qualification to routine GMP manufacturing. This role is a key leadership position within the GDE-MS&T group as we expand the commercialization of our autologous cellular biologics.
The Director will lead a team of process engineers which is responsible for overseeing the lifecycle management, process robustness initiatives, process monitoring, manufacturing technical support, including cross-departmental collaboration to enable facility fit of new technologies, development of process documentation (Batch Records, Forms, etc.), training of personnel, change control ownership, and other quality system related deliverables, as well as development and support of PPQ strategies and commercial manufacturing. The group supports these activities for multiple manufacturing nodes for vector manufacturing. This person will collaborate across all CMC functional areas to insure project advancement, rapid and best in class execution, and communication of challenges/opportunities. This position reports to the Senior Director of GDE-MS&T.
- Lead MS&T activities at CMOs to ensure uninterrupted commercial vector manufacturing and supply.
Leads, Manages, and Coaches a group of process engineers.
- Provide technical process leadership for routine commercial batches and on time closure of all quality system records such as deviations, CAPAs, and change controls.
Lead the development, understanding, and management of tools/templates to monitor vector manufacturing process performance and lead the understanding and improvement of process capability across multiple manufacturing sites.
- Deliver the implementation and execution of process control strategies, including execution of process risk assessments and continued process verification (CPV), thereby ensuring the manufacturing process is in a state of control and consistent across multiple manufacturing sites.
Ensuring compliance with internal standards and regulatory requirements for process and production related investigations.
- Develop and maintain strong relationships with external CMOs and their vendors.
Ensure permanent inspection readiness and actively support regulatory inspections.
- Lead and deliver on harmonization across the cell therapy manufacturing network.
Share operational best practices and process learning with the rest of the manufacturing network.
Qualifications & Experience
- Biochemical, Chemical, Biomedical Engineering or Cell Biology/Immunology discipline with
- B.S. with 17+ years of relevant experience
- M.S with 14+ years of relevant experience
- Ph.D. with 12+years of relevant experience
- Experience with cellular therapies is desired but not required.
- Prior people management experience desired.
- Experience should include technical support of a cGMP manufacturing facility, including strong knowledge and engineering leadership for commercial manufacturing support and technology transfer.
- Flexibility to work within manufacturing schedules and ability to travel frequently (30%).
- Ability to work in a self-driven, performance/results oriented, fast paced matrix environment. Excellent communication, writing, sense of urgency, teamwork, and presentation skills.
- Proven project management skills (organization, collaboration, multi-tasking and communication), attention to detail, and the ability to perform well in a team-based environment are required
- Strong interpersonal skills required to work with teams in different functions and organizations.
- Demonstrated ability to effectively work in cross functional teams, meet deadlines, and prioritize multiple projects
- Proficiency utilizing MS Office products and working knowledge of statistical software (R, JMP, Minitab) strongly suggested
- Detail oriented with excellent verbal and written communication skills.
- This position is primarily an office-based role and requires repetitive use of hands and wrist (computer work), and infrequent lifting of items not to exceed 50 lbs.
- Occasional bending, twisting and stooping to allow for gowning into classified environment required.
- Travel 30% of the time possible.
The starting compensation for this job is a range from $182,000 –$229,000, plus incentive cash and stock opportunities (based on eligibility).The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed.Final, individual compensation will be decidedbased on demonstratedexperience.
Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our https://careers.bms.com/working-with-us.
Benefitofferingsare subject to the terms and conditions of the applicable plans then in effectand may include the following: Medical, pharmacy, dental and vision care. Wellbeing supportsuch asthe BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support.Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility.Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.
Why You Should Apply
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.
To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation.Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment.This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to firstname.lastname@example.org. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
Bristol Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.
At Bristol Myers Squibb, we believe in the power of science to address some of the most challenging diseases of our time. Our focus on these unmet needs comes during a remarkable time, when unprecedented scientific breakthroughs are advancing the treatment of disease as never before in human history.
We work every day to transform patients’ lives through science. Each day, our employees around the world work together for patients – they are at the center of everything we do. They inspire us. They are the reason we come to work each day.
We combine the agility of a biotech with the reach and resources of an established pharmaceutical company to create a global leading biopharma company powered by talented individuals who drive scientific innovation.
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