Senior Research Scientist I, Drug Metabolism and Pharmacokinetics (DMPK)
United States - California - Foster City
Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.Making an impact on a global scale
Inclusion is one of the company’s five core values. That’s because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.
When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossibleFor Current Gilead Employees and Contractors:
Please log onto your Internal Career Site
to apply for this job.
At Gilead we believe every employee deserves a great leader. As a people leader now or in the future, we expect that you will model and create an environment of inclusion, be intentionally focused on the hiring, development, growth and retention of talent, and empower teams to align and achieve goals.
Gilead Sciences, Inc. is a research-based biopharmaceutical company headquartered in Foster City, California, that discovers, develops and commercializes innovative medicines in areas of unmet medical need.
Together, We're Creating What's Possible! For more than 35 years, Gilead has pursued breakthroughs that were once thought to be impossible.
With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV, liver diseases, serious respiratory and cardiovascular conditions, cancer and inflammation.
The Drug Metabolism and Pharmacokinetics (DMPK) group at Gilead Sciences is seeking a candidate for the position of Senior Research Scientist. The successful candidate will serve as a subject matter expert for DMPK and PK/ PD M&S in biologics discovery and development projects. This person will work closely with other teams including biologics discovery, toxicology, clinical pharmacology, pharmaceutical sciences, and regulatory to ensure optimal leads and successful clinical evaluations. The title of the position will be commensurate with the candidate's experience.Essential Duties and Job Responsibilities:
Knowledge, Experience and Skills:
- Represent the DMPK group as a subject matter expert in biologics discovery and development projects
- Develop and execute PK/PD and M&S strategies that align with the molecule format, MOA, and indications
- Perform quantitative PK/PD analysis to support project deliverables and answer translational questions
- Collaborate with project teams, line management, and CROs to deliver high-quality reports for regulatory submissions
- Supervising of research scientists and associate scientists may be required.
- PhD in pharmacokinetics, drug metabolism, pharmacology/toxicology, immunology, bioengineering, or a related life science field with 2+ years of experience, or a MS degree with 8+ years of relevant experience in large molecule/biologics discovery and development
- Industry experience as a DMPK representative, and demonstrate proficiency in mechanistic and/or QSP PK/PD modeling and simulation
- Strong communication skills and the ability to interpret results, determine next steps, and present data effectively to project teams and senior management
- Proficiency in using routine PK and basic compartmental modeling software systems such as Phoenix/WinNonlin, ADAPT, MATLAB/Simbiology, or similar.
For jobs in the United States:
As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact firstname.lastname@example.org
for assistance.Following extensive monitoring, research, consideration of business implications and advice from internal and external experts, Gilead has made the decision to require all U.S., Canada, Australia, Singapore, and Hong Kong employees and contractors to receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.
For more information about equal employment opportunity protections, please view the 'Know Your Rights'
poster.NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACTYOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACTPAY TRANSPARENCY NONDISCRIMINATION PROVISION
Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.
Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.
For Current Gilead Employees and Contractors:
Please log onto your Internal Career Site
to apply for this job.