Pharmacometrician

Pharmacometrician
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company’s five core values. That’s because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

At Gilead we believe every employee deserves a great leader. As a people leader now or in the future, we expect that you will model and create an environment of inclusion, be intentionally focused on the hiring, development, growth and retention of talent, and empower teams to align and achieve goals.
Job Description


As a Pharmacometrician your main role should be performing a variety of pharmacometrics analyses at Gilead. You will have unparalleled opportunity to be involved with several aspects the product development process. From first-in human dose projections in partnership with DMPK through approval and post-marketing activities, you will provide input into a breadth of products across Gilead portfolio. We seek to provide a rewarding career and a continuous learning

experience.

Responsibilities

• The candidate will be exposed and mentored on the development and implementation of clinical pharmacology and modeling/simulation strategies for small/large molecules in all stages of drug development.
  
• The candidate should possess strong quantitative skills, conceptual, technical and hands on development expertise with modelling and simulation activities (population modelling, PK, E-R, literature meta-analyses, Clinical Trial Simulation, etc). The candidate should be familiar with modeling and simulation software programs such as (NONMEM, R, LATEX, MATLAB, etc). Experience on the application of physiologically based pharmacokinetic (PBPK) modeling analysis to support dose decisions in clinical trials and simulation of drug-drug interactions for quantitative risk assessment is a plus.
  
• Candidates will grow on the role with the goal of being able to anticipate problems that may occur in clinical trials and develop solutions for them using precedents or original thinking. The Pharmacometrician will work with the Clinical Pharmacologist regarding optimal implementation and conduct of clinical pharmacology studies, analysis, interpretation and reporting of clinical pharmacology summaries and modeling report to support regulatory queries, interactions and NDAs/BLAs.
  
• The candidate will contribute to and represent the department on multifunctional project teams.
  
• Excellent verbal, written, and interpersonal communication skills and ability to convey moderately complex technical information clearly to others are required.
  
• In-depth knowledge and understanding of the regulatory requirements for quantitative analysis, MIDD, and MI3 pilot programs is a plus.
  

Experience and Skills:

• Working knowledge of pharmacokinetic program and analysis software (such as WinNonlin, SAS etc.) along with PK modeling and computer skills in scientific graphing. Normally receives general instructions on non-routine work and detailed instructions on routine new assignments.
  
• Requires a basic understanding of drug development.
  
• 0+ years of experience and an MD, PhD or PharmD degree in pharmacokinetics or a related scientific discipline.
  

For jobs in the United States:

As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@gilead.com for assistance.

Following extensive monitoring, research, consideration of business implications and advice from internal and external experts, Gilead has made the decision to require all U.S., Canada, Australia, Singapore, and Hong Kong employees and contractors to receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.​

For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.

NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT

PAY TRANSPARENCY NONDISCRIMINATION PROVISION

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.






jeid-5b800653089bfb4697b86e00461cc66a