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Senior Clinical Pharmacologist II

Gilead Sciences, Inc.
Foster City, CA
Start date
Mar 26, 2023

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Clinical, Clinical Research
Required Education
Bachelors Degree
Position Type
Full time
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Job Details

Senior Clinical Pharmacologist II
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company’s five core values. That’s because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible

The Clinical Pharmacology Department at Gilead Sciences is seeking a talented scientist who is driven to understand the clinical pharmacokinetics (PK) and pharmacodynamics (PD) of new and existing compounds using state of the art modeling and simulation strategies. In this role, you will be part of a team of scientists responsible for application of quantitative approaches to drug development.

At Gilead, it's our employees' dedication to science and the lives of patients living with life-threatening diseases around the world that motivates our team to success, discovery, & curiosity. This is an opportunity to join a team as we are revolutionizing healthcare by bringing urgently needed medicines to patients in the unmet areas of HIV/AIDS, Immunology, Liver diseases, Hematology and Oncology, and more.

  • Developing pharmaco-statistical models including, exposure - response models, population PK models, etc., throughout all phases of drug development. Ability to develop or support PBPK modeling will be a plus.
  • Conduct of model-based simulations to design studies that yield high value PK/PD/PGx information to aid critical decisions in support of development and registration of therapeutics.
  • Implementing Quantitative Clinical Pharmacology aspects of regulatory strategy.
  • Working in partnership with department Clinical Pharmacologist, Bioanalytical Scientists as well as Operations/Project Management peers and cross-functional teams.
  • Authoring documents and reports including documents for submission to regulatory agencies.
  • Identifying program or study-specific issues. Working collaboratively to generate potential solutions and influence teams.
  • Present work at professional meetings and publish manuscripts in leading scientific journals.

Position Requirements:
  • In-depth conceptual, technical and hands on development expertise in the area of PK/PD or PBPK modeling and simulation.
  • A Doctorate degree or equivalent in pharmacokinetics, drug metabolism, pharmacology or an advanced quantitative discipline.
  • 7+ years of experience (industry and/or academia) in pharmacometric analyses (e.g., population pharmacokinetics, exposure-response and disease progression) using modeling software like NONMEM, Matlab, S-PLUS/R and, SAS or similar software.
  • Application of physiologically-based pharmacokinetic (PBPK) modeling analysis to support dose decisions in clinical trials and simulation of drug-drug interactions for quantitative risk assessment is a plus.
  • Ability to assess, prioritize and manage a diverse, time-sensitive workload.
  • Excellent written and presentation skills.

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As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact for assistance.

Following extensive monitoring, research, consideration of business implications and advice from internal and external experts, Gilead has made the decision to require all U.S. employees and contractors to receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.​

For more information about equal employment opportunity protections, please view the ‘EEO is the Law' poster.



Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:

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Gilead Sciences is a biopharmaceutical company that discovers, develops, and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide. Headquartered in Foster City, California, Gilead has operations in North America, Europe and Australia.

Find Us
333 Lakeside Drive
Foster City

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