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#Senior Scientist I - Purification Process Development

Employer
AbbVie
Location
Worcester, Massachusetts
Start date
Mar 25, 2023

Job Details

  • The Senior Scientist will play a key role in the developing downstream purification process development for various modalities such as mAbs, ADCs, biospecifics, gene therapy, etc. Ideal candidate will conceive and implement novel experimental and/or modeling approaches to answer scientific questions. The mission of this team is to address challenging problems in biologics development areas by working collaboratively and cross-functionally by developing appropriate tools and technologies to enable right at first pass scale-up and technology transfer of various biologics modalities drug substance processes.  

  • Develop recovery and purification process that utilizes clarification, chromatography, and membrane filtration technologies for monoclonal antibodies, bispecifics and antibody drug conjugates (ADC)

    Proactively seek opportunities to come up with innovative solutions to cater challenging business problems through creative solutions

    Design and execute process development and characterization activities, impurity and viral clearance studies

    Provide deeper understanding of process performance using appropriate experimental and modeling tools

    Responsible for technology transfer to pilot lab and cGMP manufacturing facilities, troubleshooting and investigation activities

    Harness power of strong fundamentals to come up with innovative process and/or equipment designs in a strongly collaborative environment

    Build experimentally verified fit for purpose mathematical models for downstream purification processes

    Routinely demonstrate scientific initiative and creativity in research or development activities

    Exhibit a strong motivation to implement and advance various innovative technologies in relevant areas across AbbVie

    Highly independent and productive in performing laboratory research or method development, requiring only minimal direction from or interaction with supervisor

    Formulate conclusions and design follow-on experiments based on multidisciplinary data

    A primary author of publications, presentations, regulatory documents and/or primary inventor of patents

    Maintain a high level of productivity in the lab and/or pilot plant and cGMP manufacturing facilities

    Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, GxP compliance, and animal care where applicable 


    Bachelor’s Degree or equivalent education and typically 10 years of experience, Master’s Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary

    Education background in chemical engineering, biomedical engineering, biochemistry, biochemical engineering, or biotechnology is preferred

    Experience in areas of purification process development is preferred 

    Demonstrate excellent communication skills and specifically illustrate strong oral and written technical communications

    Seamlessly present research outcomes to multifunctional teams  

    Play a strong team player in a cross functional collaborative environment thriving for world class excellence and maintains strong working relationships with internal, global, and external collaborators

    Demonstrated problem-solving skills and capability to overcome complexed issues

    Demonstrated success in coordinating and executing important projects to achieve business goals

    Must have a “results-oriented” work ethic and a positive “can-do” attitude with a strong sense of urgency and self-motivated desire to achieve

AbbVie is an equal opportunity employer including disability/vets. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a disabled veteran, recently separated veteran, Armed Forces service medal veteran or active duty wartime or campaign badge veteran or a person’s relationship or association with a protected veteran, including spouses and other family members, or any other protected group status. We will take affirmative action to employ and advance in employment qualified minorities, women, individuals with a disability, disabled veterans, recently separated veterans, Armed Forces service medal veterans or active-duty wartime or campaign badge veterans. The Affirmative Action Plan is available for viewing in the Human Resources office during regular business hours.


Company

AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, and YouTube.

Stock Symbol: ABBV

Stock Exchange: NYSE

Company info
Website
Phone
1-800-255-5162
Location
1 North Waukegan Road
North Chicago
Illinois
60064
US

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