Advisor, In Vivo Pharmacology

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Organization Overview

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Lilly is passionate about the discovery, development and commercialization of potential new medicines that will impact and improve the lives of patients. Our Lilly Genetic Medicines (LGM) team is an innovation-focused organization striving to identify, develop and apply the most groundbreaking technologies to deliver maximum benefit to our patients. Our agile and diverse team strives to operate as an autonomous ‘biotech-like’ company within the walls of Lilly.

Our rapidly expanding Lilly Genetic Medicines (LGM) in Indianapolis is seeking to grow our in vivo pharmacology capabilities. Our team works cross-functionally with multiple therapeutic modalities and the ideal candidate for this position will help support efforts in diverse genetic medicines and targets. Our goal is to deliver on the promise of durable genetic medicines to patients. This position will be based in Indianapolis, IN and located at Lilly Corporate Center.

Position Summary

The in vivo pharmacology Advisor will participate and contribute to the LGM in vivo pharmacology lab, to lead efforts to support the discovery and optimization of novel therapeutic candidates for genetic medicines.

Responsibilities

• Design and implement in vivo pharmacology experiments to characterize activity of genetic medicines in mouse models
• Lead efforts for development, characterization, and validation of novel in vivo models
• Design and conduct studies to investigate in vivo distribution and clearance of genetic medicines
• Establish and manage Animal Care and Use Protocols in accordance with IACUC guidelines.
• Actively mentor and develop in vivo lab associates
• Oversee data analysis, result interpretation, and communication to internal stakeholders and ensure accurate recordkeeping
• Prioritize projects and allocate workload accordingly to ensure appropriate resourcing to meet personnel and project needs
• Collaborate with cross-functional partners (Preclinical, toxicology, PK/PD modelling) to ensure translation from discovery to development and to drive innovation

Basic Qualifications

• PhD in neuroscience, biology, or related discipline
• 2-5+ years of relevant in vivo experience (academic or industry).
   

Additional Skills/Preferences

• Expert in vivo skills including rodent handling, dosing (IV, SC, IP, PO, etc.) and harvesting tissues/fluids
• Candidates with experience doing microdissection or surgery, or stereotaxic surgery are strongly preferred
• Prior experience in macromolecule distribution and metabolism
• Experience with ex-vivo assays is a plus such as ELISAs, WB, qPCR and histology techniques
• Passion, knowledge and experience in neuroscience or rare disease research
• Strong analytic thinking skills. Demonstrated ability to articulate issues, and extract and synthesize complex issues into key focus
• Strong inter-personal and communication skills. Proven record to collaborate and network across a wide variety of functions and work effectively with internal and external partners
• Excellent organizational skills with the ability to work in a fast-paced team environment, meet deadlines, maintain detailed documentation, and prioritize work on multiple projects

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law). 

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