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Research Associate II, Neuromuscular and Cardiac Biology

Employer
Entrada Therapeutics
Location
Boston, MA
Start date
Mar 25, 2023

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Discipline
Regulatory, Science/R&D, Biology, Research
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Genetown, Best Places to Work

Job Details

The Organization

What's happening at Entrada Therapeutics? Our mission is to transform the treatment of devastating diseases and improve patients' quality of life using intracellular biologics. Leveraging our proprietary Endosomal Escape Vehicle (EEV)™ platform, we are creating and advancing a diverse pipeline of oligonucleotide, enzyme, protein, and peptide programs to efficiently target and engage underlying drivers of diseases.

Our novel approach to drug design and delivery addresses current challenges associated with both large and small molecule therapeutics and represents a fundamental advancement in the field of intracellular biologics.

We're a tight-knit team of experts and leaders in both therapeutics development and rare disease and are excited to grow and attract colleagues who are ready to join a high energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.

The Perfect Fit

You should be versatile, self-motivated, and looking forward to rolling up your sleeves, as you will be involved in all aspects of neuromuscular and cardiac biology. Your team player mentality and excellent communication skills will allow you to collaborate effectively as you work alongside your team as well as cross-functionally.

The Opportunity

In this position, you will be part of a cross-functional team exploring new therapeutic programs for neuromuscular and cardiovascular disease areas. You will play a critical role in the development and execution of molecular and cellular biology experiments which are critical to the success of our drug discovery programs. You will utilize cell-based disease models, and techniques such as PCR, Western blot, cell and tissue culture, and immunostaining (IHC, IF). 

Responsibilites

  • Responsible for maintaining and expanding mammalian cell lines
  • Screening compounds in cells, processing samples and performing downstream analyses
  • Interpret and present research data and findings in internal scientific meetings
  • Effectively collaborate and communicate in a fast-paced, multi-disciplinary environment
  • Be scientifically curious and self-driven with good time management skills
  • Support general lab functions and perform regular equipment maintenance
  • Document work in a well-maintained lab notebook
The Necessities

At Entrada, our passion for science, our devotion to patients and our values drive our behavior:

  • Humanity - We genuinely care about patients and about one another.
  • Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
  • Creativity - We are creative problem solvers.
  • Collaboration - We are more than the sum of our parts.
  • Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

  • B.S./M.S. in Molecular/Cellular biology or a related field with 2+ years of relevant academic or industry experience
  • It is highly desirable that you come with hands-on experience with in vitro models of skeletal/cardiac muscle
  • We would love for you to have a foundational knowledge of skeletal/cardiac muscle biology, but by no means is it required!
  • You should have excellent verbal and written communication skills– you will have a lot of opportunities to demonstrate this every day!
The Perks

By becoming a team member here at Entrada, you’ll have access to competitive health, dental, and vision coverage, as well as life insurance, and short term and long-term disability insurance. We value work life balance, you'll benefit from discretionary time off, paternity leave, and an excellent 401(k) package. We also offer a generous transportation stipend to commute as you wish. Our location in the vibrant and growing Seaport District is close to all the best that the city of Boston has to offer.

Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law.

Third Party Staffing Agencies

Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.

 

Company

Entrada Therapeutics is a biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines, Endosomal Escape Vehicle (EEV™) therapeutics, to engage intracellular targets that have long been considered inaccessible and undruggable. The Company’s EEV therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues with an improved therapeutic index. Through its proprietary, highly versatile and modular EEV platform, Entrada is building a robust development portfolio of oligonucleotide-, antibody- and enzyme-based programs for the potential treatment of neuromuscular diseases, immunology, oncology and diseases of the central nervous system. The Company’s lead oligonucleotide programs include ENTR-601-44 targeting Duchenne muscular dystrophy (DMD) and ENTR-701 targeting myotonic dystrophy type 1 (DM1).

Stock Symbol: TRDA
Stock Exchange: NASDAQ

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Find Us
Website
Location
6 Tide Street
Boston
Massachusetts
02210
US

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