Engineer II, Process Development

The Role:

Moderna is working to develop first-in-class messenger RNA (mRNA) based medicines. We are seeking a highly skilled and motivated Engineer or Research Associate/Sr. Research Associate to join Modernas Technical Development organization in Norwood, MA.

This role will support the development of manufacturing processes for Modernas mRNA-based medicines to enable clinical and commercial supply, with a focus on process understanding and process control strategy definition, and the optimization, transfer, and characterization of manufacturing processes. The role will additionally interface with and support cross-functional teams across CMC, Research and Development, Pre-clinical and Clinical Manufacturing, Quality, and Analytical Development.

Applicants must have demonstrated experience in designing, executing, and analyzing scientific experiments. Relevant academic and/or industrial experience in drug substance or drug formulation/delivery development is ideal. Previous experience with chromatography, nanoparticle formulations, filtration technologies, mixing technologies, and/or statistical design of experiments is preferred.

Applicants should enjoy working in a fast-paced, dynamic, and innovative environment. Collaboration through cross-functional matrix teams is required. Applicants must have exceptional time management and communications skills, with a strong attention to detail.

Heres What Youll Do:

• Design, execute, and analyze experiments for existing and novel process modes

• Develop commercial manufacturing processes, characterize the process design space, and define critical process parameters

• Collect, archive, process, and organize samples for downstream analyses

• Maintain good documentation practice through electronic lab notebooks and technical reports

• Clearly communicate results to a wide audience, both internally and cross-functionally

• Execute and troubleshoot standard protocols, and develop and adapt new protocols into practice

• Maintain positive relationships with internal business partners to facilitate collaborative development across all functions

• Deliver reproducible and impactful results under ambitious timelines

Heres What Youll Bring to the Table:

• BS or MS in chemical engineering, biological engineering, chemistry, biochemistry, or closely related field

• BS/MS with 0-3 years of relevant industry experience in bioprocess development

• Hands-on experience with chromatography, ultrafiltration, normal flow filtration, and development of innovative unit operations

• Working knowledge of statistical design of experiments (DoE) and analysis of multivariate data

• Excellent technical writing and verbal communication skills

• Strong interpersonal skills in dynamic settings

• Preferred: Experience in nucleic acid drug development (DNA, RNA, oligonucleotides) and/or nanoparticle delivery.

• Preferred: Experience with analytics and biophysical characterization of nanoparticles

• Preferred: Knowledge of cGMP, ICH, regulatory guidelines and QbD principles as they apply to risk management and product commercialization

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

• Highly competitive and inclusive medical, dental and vision coverage options
• Flexible Spending Accounts for medical expenses and dependent care expenses
• Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
• Family care benefits, including subsidized back-up care options and on-demand tutoring
• Free premium access to fitness, nutrition, and mindfulness classes
• Exclusive preferred pricing on Peloton fitness equipment
• Adoption and family-planning benefits
• Dedicated care coordination support for our LGBTQ+ community
• Generous paid time off, including:
  Vacation, sick time and holidays
  Volunteer time to participate within your community
  Discretionary year-end shutdown
  Paid sabbatical after 5 years; every 3 years thereafter
• Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
• 401k match and Financial Planning tools
• Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
• Complimentary concierge service including home services research, travel booking, and entertainment requests
• Free parking or subsidized commuter passes
• Location-specific perks and extras!

Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible. Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.

About Moderna

In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit www.modernatx.com.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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