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Director, Translational Medicine, Rare Disease

Moderna, Inc.
Cambridge, MA
Start date
Mar 25, 2023

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Science/R&D, Pathology
Required Education
Masters Degree/MBA
Position Type
Full time
Genetown, Best Places to Work

Job Details

The Role:

Moderna is rapidly growing a portfolio of transformational mRNA-based therapies in various disease areas. To optimize portfolio delivery, we are building a Translational Medicine team in Therapeutics. The Director Translational Medicine, Rare Diseases, is a strategic and creative thinker and passionate drug developer who will collaborate to unlock the full potential of mRNA therapeutics in close collaboration with non-clinical and clinical teams through development of innovative translational clinical strategies. This role is reporting to the VP Translational Medicine, Therapeutics, and is located in Cambridge/MA or Princeton/NJ.

Heres What Youll Do:

  • You will be a champion of translational thinking and together with non-clinical and clinical leaders at Moderna will define and support the right cross-departmental collaborations, dialogue and process to ensure world leading translational practices

  • As part of project teams, you define and continuously evolve strategic biomarker plans that will allow data-driven decision making, acceleration through the clinical development stages, and exploration of stratification opportunities

  • You will participate in the generation of clinical trial designs participate in writing of key documents, e.g. Clinical Protocols and IBs.

  • You will conceive, plan and execute observational/mechanistic clinical work to support projects and the therapeutic area

  • Through your involvement in multiple projects and critical analysis of emerging clinical data, you will contribute to the continuous maturation of the Rare Disease TA strategy

  • You will expand the Moderna TM toolbox through exploration of innovative techniques with internal experts and an external network of advisors

  • Together with the VP of TM, you will further refine the composition and responsibilities of the TM team to ensure optimal integration in the Moderna structure and support of Moderna mindsets

  • This is not a bench research role.

Heres What Youll Bring to the Table:

  • Curiosity, Creativity, and Passion to develop life changing therapies

  • An advanced Degree (PhD, MD, MD/PhD, PharmD) and a solid scientific background in Rare Diseases

  • A translational mindset that is based on 5 years experience in Pharma/Biotech Drug Development and experience in building clinical biomarker strategies

  • Translational Medicine is a team sport you need excellent communication skills and the ability to collaborate effectively in a dynamic, cross functional environment

  • Academic or Industry experience in Rare Diseases and Metabolism

  • Solid understanding of biomarker modalities, concepts, state of the art technologies and innovative data analysis

  • Experience in conceiving and conducting observational and/or mechanistic clinical studies to support the TA and projects

  • Flexibility Moderna is an exciting and rapidly evolving company

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

  • Highly competitive and inclusive medical, dental and vision coverage options
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
  • Family care benefits, including subsidized back-up care options and on-demand tutoring
  • Free premium access to fitness, nutrition, and mindfulness classes
  • Exclusive preferred pricing on Peloton fitness equipment
  • Adoption and family-planning benefits
  • Dedicated care coordination support for our LGBTQ+ community
  • Generous paid time off, including:
    Vacation, sick time and holidays
    Volunteer time to participate within your community
    Discretionary year-end shutdown
    Paid sabbatical after 5 years; every 3 years thereafter
  • Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
  • 401k match and Financial Planning tools
  • Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
  • Complimentary concierge service including home services research, travel booking, and entertainment requests
  • Free parking or subsidized commuter passes
  • Location-specific perks and extras!

Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible. Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.

About Moderna

In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.



Moderna is advancing messenger RNA (mRNA) science to create a new class of transformative medicines for patients. Moderna’s platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, providing the Company the capability to pursue in parallel a robust pipeline of new development candidates. Moderna is developing therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases and cardiovascular diseases, independently and with strategic collaborators.

mRNA is now a turning point in the history of science, medicine, technology, even humankind itself. With this breakthrough discovery, many of the world’s biggest and most challenging medical problems are no longer a question of “how?” but merely a question of “when?”

Come with us as we pursue the uncharted reaches of possibility and make your mark on the future of medicine.


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