Scientist I, Biology

About Maze Therapeutics

Maze is a clinical-stage biopharmaceutical company harnessing the power of human genetics to transform the lives of patients through the development of a pipeline of novel precision medicines for patients with genetically defined diseases. Maze is leveraging Compass™, a proprietary, end-to-end purpose-built platform to advance a pipeline of precision medicines across four disease areas - renal, cardiac, neurological and metabolic diseases. Our flexible business model aims to translate our genetic insights into new therapies for patients as possible.

Our People

Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative, and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients. 

Our Core Values

Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission.  

Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others. 

Stand True – Our integrity is foundational; it guides us no matter the obstacle.  

Role Description:

The biology team is seeking a talented and highly motivated scientist that will play an integral role in both investigating early targets and in vitro pharmacology. This is a lab-based role focused on mechanistic interrogation of targets identified using the Compass™ platform as well as supporting drug discovery activities. The ideal candidate is a team player who is independent, enjoys problem solving, and is comfortable applying new techniques while working in the new target space. Experience with biochemical and cell-based assays, tissue culture, and immunoassays are essential. Experience with target validation and assay development to support drug discovery are preferred. Experience with automation and high-throughput screening is a plus. The candidate will also be expected to work effectively cross-functionally with colleagues from diverse disciplines and to present experimental findings to others.

Your Impact Includes:

• Supporting target validation and interrogation of biological mechanism through biochemical and cell-based experimentation
• Independently developing and optimizing robust biochemical and cell-based assays to support drug discovery
• Reliably executing established standardized assays to support active programs
• Clearly and concisely presenting data and findings to the project team
• Collaborating closely with other scientists in Biology and across the project team

Qualifications:

• B.S. with 7+ years or M.S. with 5+ years of lab experience in a biotechnology, pharmaceutical, or academic setting
• Experience in a drug discovery environment is preferred
• Ideal candidates will have a depth of research experience in biochemical and cell-based assay development and a broad range of additional laboratory skills
• Experienced with standard biological laboratory techniques (e.g., western blots, qPCR, plate-based assays, mammalian cell culture) is required.
• Experience with automation and high-throughput screening is a plus
• Excellent data analysis skills and experience with a variety of scientific software applications is required
• Ability to adapt to changing project needs and eager to learn new skills
• Independently plan and execute daily activities, detail oriented, strong written and verbal communication skills, strong collaborative spirit, good record keeping

The expected salary range for this role for employees located in the San Francisco bay area is $123,500 - $147,300. Additionally, this position is eligible for an annual performance bonus. 

Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills and job location. The expected salary range for this role may be modified in the future. 

Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.