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Senior Analyst, Quality Control Analytical

Senti Biosciences
Alameda, CA
Start date
Mar 23, 2023

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Information Technology, Business/Data Analytics, Quality
Required Education
Bachelors Degree
Position Type
Full time
Biotech Bay

Job Details

Thank you for your interest in a career at Senti Biosciences. Our mission is to create a new generation of smarter medicines that outmaneuver complex diseases in ways previously inconceivable. We are passionate about designing gene circuits to improve the “intelligence” of cell and gene therapies in order to enhance their therapeutic effectiveness against a broad range of diseases that conventional medicines are unable to address.
At Senti, we find purpose and meaning knowing that our efforts have the potential to improve the lives of patients and their families with more effective and safer treatment options. With science as our foundation and empathy as our key guiding principle, colleagues become friends, managers become mentors, and with time, cancer becomes history.

This position is reporting to Sr. QC Manager and responsible for supporting Quality Control bioanalytical testing for in-process, release, and stability testing of clinical cell therapy drug products. Additionally, the Senior Analyst QC may assist with investigations and continuous improvement efforts. 
  • Perform bioanalytical testing and data review of in-process, batch release, and stability samples of cell therapy drug product in accordance with applicable procedures and cGMP requirements.
  • To be the qualified trainer on analytical methods to junior analysts
  • To be SME for QC analytical methods in support of non-GMP and GMP products
  • Lead method qualification efforts, method and system troubleshooting, method optimization…
  • Ensure timely completion of testing and tasks as assigned.
  • Review and Trend data obtained from product testing
  • Train on additional test methods and provide support to a broader spectrum of testing responsibilities.
  • Lead investigations through data gathering or interview process for root cause analysis and product impact.
  • Author and Revise SOP’s, protocols, technical reports...
  • Apply scientific principles to analytical testing and the proper use of laboratory equipment.
  • Communicate effectively with management regarding task completion, roadblocks, and needs.
  • Expected to participate in projects and continuous improvement efforts.
  • Perform other tasks as assigned.
  • Support for QC and manufacturing operations requires shift coverage consisting of weekdays, weekends, holidays, and during adverse weather conditions.

  • BS degree in chemistry, biology, or related disciplines with 5-6 years of experience required, a Master’s degree is preferred.
  • Must have at least 3 to 4-year experience in pharmaceutical industry supporting cGMP areas
  • Must have GMP laboratory, molecular and cell based experience. This may include Flow Cytometry, qPCR, digital PCR, cytotoxicity assays, ELISA/Luminex assays and cell counting.  
  • Must have experience in writing and /or authoring protocol, SOPs, report and data trending
  • Must be meticulous, detail oriented, and analytical.
  • Must be highly motivated, have excellent organizational, communication and interpersonal skills.
  • Must be able to work independently and as part of a multi-disciplinary team.

Salary and Benefits:
  • Compensation for this role includes base salary, annual target bonus and equity
  • The base salary range for this role is $90,000 - $105,000. Starting pay is determined by multiple job-related factors including a candidate’s skills, education and experience level, benchmark, and internal parity
  • Significant growth opportunity as the company expands
  • Empathetic, supportive and collaborative colleagues and work environments

Senti Bio is a publicly traded (Nasdaq: SNTI) gene circuit company headquartered in South San Francisco. Our mission is to create a new generation of smarter medicines that outmaneuver complex diseases using novel and unprecedented approaches.

We are committed to an inclusive and diverse Senti Bio. We believe that different perspectives lead to better ideas, and better ideas allow us to better understand the needs and interests of our diverse Senti Team. We welcome people of different backgrounds, experiences, abilities and perspectives and are an equal opportunity employer.


Senti Biosciences is a next-generation therapeutics company that is developing gene circuits and programming cells for tremendous therapeutic value. Senti’s mission is to outsmart complex diseases with more intelligent medicines that will transform people’s lives. By programming cells to respond, adapt and make decisions, Senti is creating smarter therapies with computer-like logic, enhanced functionality and greater therapeutic control.

Senti’s product candidates address major challenges in cancer treatment. To overcome cancer immune evasion, Senti is building cell therapies equipped with combinatorial arming gene circuits to elicit broad and sustained anti-tumor immune responses. Senti is also developing next-generation cell therapies that more precisely target and eliminate cancer cells while sparing healthy tissue.

Senti Biosciences is based in South San Francisco and was founded in 2016 by Drs. Tim Lu, Philip Lee, Jim Collins and Wilson Wong. Senti is proud to count NEA, 8VC, Amgen Ventures, Lux Capital, Menlo Ventures, Pear Ventures, Allen & Company, Nest.Bio, Omega Funds, and LifeForce Capital among its investors.



Find Us
2 Corporate Drive, First Floor
South San Francisco

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