Associate Scientist / Scientist, Protein Sciences

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Adicet Bio, Inc. is a clinical stage biotechnology company discovering and developing allogeneic gamma delta T cell therapies for cancer. Adicet is advancing a pipeline of “off-the-shelf” gamma delta T cells, engineered with chimeric antigen receptors (CARs) and adaptors (CAds), to enhance selective tumor targeting and facilitate innate and adaptive anti-tumor immune response for durable activity in patients. For more information, please visit our website at https://www.adicetbio.com.

ASSOCIATE SCIENTIST / SCIENTIST, PROTEIN SCIENCES

Adicet Bio is seeking a highly motivated team member who will be a significant contributor to the protein sciences team. This person will work with other members of the team to design and optimize approaches to create customized Antibody conjugations to a variety of PEG, hydrogel, and nanoparticle scaffolds. The candidate will also contribute to routine expression, purification, and characterization for a wide variety of ongoing pipeline projects. The ideal candidate will have excellent communication skills and a desire to mentor other scientists at the bench.

Key responsibilities:

• Work alongside other team members in protein sciences to express, purify, and characterize diverse proteins ranging from antibodies to antigens to engineered protein molecules for ongoing programs in research. ?
• Lead efforts to design and implement novel conjugating antibodies and/or proteins to beads or other small molecules.
• Develop assays to characterize the properties of Antibody-PEG conjugates and/or hydrogels.
• Train and serve as a mentor for other scientists on the team.
• Maintain updated lab notebook and records.

Qualifications:

• At least 3-5 years of experience in closely related field required. Title will be dependent on previous experience.
• BS in chemistry, biochemistry, or chemical biology. Master’s degree preferred but not required.
• Strong desire to work at the bench.
• ands-on experience performing and/or optimizing purification strategies for challenging proteins.
• Prior hands-on experience performing protein conjugations for ADC development a strong bonus.
• Previous hands-on experience conjugating proteins to fluorophores, PEGs, or nanoparticles.
• Experience with site-specific protein conjugations or ADCs a bonus.
• Previous experience and/or familiarity with HPLC-SEC (Agilent), FPLC (AKTA Pure or Avant), MALS (Wyatt).
• Desire to work in a fast-paced environment on challenging research projects.
• Prior experience in mammalian cell culture (293 or CHO).
• Highly organized and detail oriented.
• Ability to manage multiple projects and collaborate efficiently with cross-functional teams.?

Adicet Bio requires all workers to be fully vaccinated against COVID-19, including the booster dose.

At Adicet, our people are our greatest focus. We believe that attracting and retaining the best and brightest is the key to achieving our mission to deliver best-in-class gamma delta T cell therapies for patients fighting cancer.

We offer a competitive compensation package including base salary, annual cash bonus, long-term incentives (equity), Employee Stock Purchase Plan (ESPP) and a 401(k) with ROTH and a 4.5% Company match.

To ensure the wellness of our employees and their loved ones, we offer comprehensive health plans (medical, dental, vision, etc.), Flexible Health and Commuter Spending Accounts (FSA) and a company matched Health Savings Account (HSA). We also offer a life, AD&D, short and long-term disability insurance, and legal, pet, and various other voluntary insurance programs.

We also believe our greatest ideas come when we are refreshed and focused, and we offer generous paid time-off including 12 company holidays with end-of-year shutdown, vacation, sick time, and paid parental leave.

Adicet is located in a state-of-the-art facility and works to create an incredible office experience with an onsite gym and various other fitness options, abundant, zero-cost, onsite parking with electric vehicle charging stations and free shuttle (Caltrain), company subsidized lunches (delivered onsite daily) and fully stocked breakrooms.

In compliance with California’s pay transparency law and in pursuit of pay equity and fairness, we publish salary ranges for all open positions. The pay scale range for this role is $ 105,000.00 - $145,000.00 annualized base salary. The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to, their qualifications (education, experience, specialty, and training), and peer and market data. This listed salary range represents the Company’s good faith and reasonable estimate of the range of possible compensation at the time of posting.