Senior Scientist / Principal Scientist, Immunology, Oncology Cell Therapy Innovation

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Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine?

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Here, you will be a vital contributor to our inspiring, bold mission.

The vision of Takeda is to build a world-class Cell Therapy team and deliver allogeneic innate cell therapy product to bring hope to both hematological and solid tumor patients. Oncology Cell Therapy Innovation is missioned to develop innovate innate cell platform and novel engineering approaches to drive discovery pipeline for Takeda Cell Therapy.

ROLE OVERVIEW:

This position is seeking experienced and highly motivated immunologist, who has a solid background in immunology, especially immune-oncology and innate cell immunology, to join Cell Therapy Discovery team. The successful candidate will play an important role in optimizing cell therapy platforms, e.g., CAR-NK, CAR-γδT, to improve the biological function (potency and persistence) of cell therapy products, based on solid understanding of innate cell biology, i.e. immune cell activation, survival, proliferation, and function, and cancer/immune biology in tumor microenvironment. The scientist will lead discovery projects and collaborate with colleagues within department and cross-function teams to drive the development of Cell Therapy discovery platforms.

KEY RESPONSIBILITIES:

• Contribute to discovery projects by independently designing and developing well-defined mechanistic experiments and projects within oncology cell therapy research.
• Lead from the lab to advance novel and differentiated cell therapy products toward clinical milestones, by working collaboratively with internal cross-functional teams and external partners.
• Design, execute, and interpret functionalin vivo,in vitro, andex vivoassays to understand the mechanism-of-action and play an active role in subsequent scientific discussions to drive decisions.
• Propose novel projects based on internal results, external partners, and published reports and demonstrate leadership through effective communication of study plans/value, and research results.

EDUCATION, EXPERIENCE, KNOWLEGE AND SKILLS:

• Ph.D. in Immunology, Biology, Biological/Chemical Engineering, or related discipline.
• Minimum of 5+ years relevant pharmaceutical industry/academic experience post-graduation

• Hands on experience with CAR-T, CAR-NK, CAR-γδT, TCR-T cell therapies / immunotherapies, including cell culture, immune cell activation/expansion, viral transduction for various types of immune cells.
• Profound skills in in vitro and in vivo immune cell characterization and function assessment, such as, multi-color flow immunophenotype, multiplex cytokine measurement, cytotoxicity assay, and other molecular based assays.

• Excellent written and verbal communication skills, detail-oriented organization skills, and team collaboration skills.
• Track record of publications to demonstrate scientific establishment.

TRAVEL REQUIREMENTS:

• May require approximately up to 0-5% travel.

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

WHAT TAKEDA CAN OFFER YOU:

• 401(k) with company match and Annual Retirement Contribution Plan
• Tuition reimbursement Company match of charitable contributions
• Health & Wellness programs including onsite flu shots and health screenings
• Generous time off for vacation and the option to purchase additional vacation days
• Community Outreach Programs

Base Salary Range: 130,200.00 to 186,000.00. Employees may also be eligible for Short Term and Long-Term Incentive benefits. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off.

The final salary offered for this position may take into account a number of factors including, but not limited to, location, skills, education, and experience.

Empowering Our People to Shine

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EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.