Research Associate I/II, Formulations

Who We Are:

We are a clinical stage company powering the next wave of genetic medicine through superior delivery with our next-generation lipid nanoparticle delivery platform. Our mRNA and gene editing therapeutics have the potential to directly replace or address underlying genetic mutations in a vast range of diseases starting with primary ciliary dyskinesia and cystic fibrosis. Our selective organ targeting (SORT) LNP platform is uniquely differentiated to enable the delivery of diverse genetic payloads to tissues beyond the liver.

At ReCode, we bring a unique blend of rigor, creativity, and curiosity to our high-hurdle mission. Our team is uniquely positioned to tackle this challenge, given our extensive experience in lipid nanoparticle delivery, mRNA design and optimization, mRNA manufacturing, gene editing, and rare disease drug development. We are a high performing, highly functional organization with a culture that is caring and strives to enable every member of our team to thrive.

Summary of Position:

The Research Associate will work as part of a team, under the direction of the group leader/manager, to conduct laboratory experiments to support the development of robust scalable LNP-encapsulated nucleic acids formulations and manufacturing processes, including lab-scale process development, process scaleup, and in-process characterization. The Research Associate will have the opportunity to work as an integral part of a talented, diverse team of scientists, and develop career in the exciting field of RNA therapeutics. The ideal candidate will be proactive, enthusiastic, and show a passion for LNP-RNA formulation and process development. The applicant should have strong communication and collaboration skills, along with a background in LNP formulation and process development.

Responsibilities:

• Executes studies to define formulation components, vehicle, and primary container.
• Operates common biopharmaceutical unit operations such as mixing, dialysis, tangential flow filtration, and sterile filtration.
• Performs in-process characterization such as pH, particle size, encapsulation efficiency measurement etc.
• Supports troubleshooting and technical investigations as needed.
• Responsible for executing or supporting experiments to meet agreed upon deliverables and timelines.
• Maintain thorough and detailed electronic lab notebooks and documentation records.
• Support and participate in R&D and project management meetings.
• Adhere to all laboratory safety requirements and procedures.
• Assist in maintaining general laboratory functionality and lab equipment.
• Assist in ordering and receiving of lab supplies.

Qualifications:

• B.S. or M.S. Chemical Engineering, Chemistry, Bioengineering, Material Sciences, Pharmaceutical Sciences or related scientific with laboratory experience (ideally in organic chemical synthesis, nanoparticles, formulation development, nucleic acids, drug delivery)
• Strong written and oral communication skills, comfort with a "start-up environment"

Salary Range: *

*70-73k- Please note that for remote positions, salary may be adjusted for cost of living

Benefits Offered:

• No premium cost for employees - 100% subsidized by ReCode for full-time employees
• Company 401k contribution
• 15 days of company paid holidays, including a holiday shutdown (usually the last week of the year)
• Mental health support for employees & their families
• FSA available, including a lifestyle spending account subsidized by company
• Employee discounts at hotspots

ReCode Therapeutics (www.recodetx.com) offers a competitive compensation/benefits package with a friendly, collaborative culture that values employee engagement and ongoing career development.

ReCode Therapeutics is an Equal Opportunity Employer.