Internship, Molecular Science
- Maze Therapeutics
- South San Francisco, CA
- Start date
- Mar 21, 2023
- Administration, Science/R&D, Biology, Molecular Biology, General
- Required Education
- Bachelors Degree
- Position Type
- Full time
- Biotech Bay
We Are Genetic Navigators bringing together passionate, creative, and dedicated scientists, professionals and students to in our mission to translate novel genetic insights into lifesaving medicines. We pride ourselves in a novel research platform for rare and common genetic based diseases with active drug programs in development. Located in South San Francisco, scientists collaborate on experimental design to discover and validate new targets of interest.
Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative, and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.
Our Core Values
Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission.
Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.
Stand True – Our integrity is foundational; it guides us no matter the obstacle.
We are seeking a talented future chemistry/protein scientist to join our molecular science team for an 8-week internship. The successful candidate will be responsible for conducting computational and wet lab experiments to facilitate endeavors in drug target characterization and/or structure-based drug discovery.
Your Role as an Intern:
- Work closely with intern mentors in Molecular Sciences
- Intern will first generate hypothesis by computational methods (e.g. AlphaFold-multimer) and validate hypothesis with biophysical techniques.
- Alternatively, intern will design RNA with the aid of computational methods and test binding of small molecules to this RNA by biophysical techniques.
- Currently enrolled in a (Bachelor’s, Master’s, Doctoral) program to complete a degree in life sciences, physical sciences, and/or computational sciences, with at least one year of (or the equivalent) upper division courses completed
- Has completed one semester/quarter of organic chemistry lab
- Familiarity with Unix command line and bash scripting. Experience programming in at least one language (e.g. Python) is strongly preferred
- Experience with molecular biology methods, such as cloning and affinity-based protein purification strongly preferred
- Self-motivated with desire to push new scientific boundaries. Solid skills to communicate scientific topics to a variety of audience and willingness to contribute as a team player
- Interest in the biotech industry, specifically a fast-paced startup
- Candidate is expected to be on-site 40 hours per 5-day work week
The expected hourly rate for this role is as follows:
Maze Therapeutics is translating novel genetic insights into lifesaving medicines, through an approach that integrates human genetics and functional genomics. Advances in these areas have enabled us to decode the mysteries of genetic modifiers in a range of severe diseases, which we aim to turn into medicines that mimic protective mutations.
What are genetic modifiers?
Despite an understanding of the genetic basis for many diseases, it remains a mystery why some people with a disease-causing mutation never get sick. This is often due to genes elsewhere in our DNA that affect the severity of disease and can provide a natural form of protection.
The Maze approach
Dramatic advances in human genetics and functional genomics now enable us to decode the mysteries of genetic modifiers in a range of severe diseases. Today, we believe we can systematically identify genetic modifiers and turn these insights into medicines. We have assembled a world-class team to realize this vision, including creative scientific pioneers, experienced company builders and biotech industry leaders.
Join us in our pursuit to change lives by translating genetic insights into medicine - view our job postings with the link to the left.
171 Oyster Point Blvd, Suite 200
South San Francisco
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