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Research Associate - Cell Culture

Employer
OmniAb
Location
Durham, NC
Start date
Mar 18, 2023

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Discipline
Regulatory, Research/Documentation, Science/R&D, Research
Required Education
Bachelors Degree
Position Type
Full time

Job Details

OmniAb’s Icagen Ion Channel Technology Center in Durham, North Carolina currently has an opening for a talented Research Associate to join our Biology team. This is a full-time, laboratory-based position offering an opportunity to play key roles in identifying novel drug candidates and advancing drug development projects. The ideal candidate will have fundamental understanding of cellular biology and hands-on experience with mammalian cell culture techniques. The successful candidate will be capable of managing multiple projects simultaneously while working as part of a core team. The work will be fast-paced and process-oriented in a dynamic environment which is predicated upon continuous improvement where everyone is encouraged to contribute to improving laboratory efficiency.

About Us:

OmniAb consists of dynamic and innovative scientists that employ a variety of novel platforms to support our partners in discovering next generation therapeutics. At the core of OmniAb is the ability to engineer animals to generate affinity matured human sequence antibodies for use in conventional and novel therapeutic formats. We leverage our proprietary animals with state-of-the-art technology in antigen design, immunization methods and high-throughput single B cell screening to facilitate discovery of best-in-class antibodies. Within OmniAb are also best-in-class capabilities for the discovery and screening in high value ion channel and transporter targets. We are looking for accomplished team players who are enthusiastic to contribute to the technological frontier of drug discovery, contribute to improving human health, and passionate in their desire to collaborate with partners to develop next generation therapeutics. See OmniAb.com for more details about the exciting science being performed at OmniAb.

Responsibilities:

  • Maintain 12-20 mammalian cell lines using aseptic technique (cell harvesting, counting, seeding for functional testing, and cell cryopreservation).

  • Responsible for cell culture maintenance, reagent preparation and purchasing, cell plating, culture expansion, cryopreservation, cell line generation, notebooks, and database upkeep.

  • Experience using hemocytometer-based cell counting technologies and performing calculations to scale-up requests.

  • Comfortable with the flexible nature of a data driven environment.

  • Proactive communication style and exceptional organizational skills, with the ability to multitask effectively.

  • Integral member of the in vitro pharmacology team supporting multiple target screening and lead drug candidate optimization projects.

  • Contribute to laboratory support duties that are associated with operating a productive pharmaceutical industry research group. 

Requirements: 

  • BS in biology or cellular/molecular biology and 0-2 years of relevant experience in a research or drug discovery laboratory environment

  • Hands-on experience with aseptic techniques related to mammalian cell culture (experience with Cho and Hek293 base cells lines)

  • Experience using lab automation and electronic multichannel pipettors preferred

  • Strong ability to multi-task and willingness to work effectively across teams in a highly collaborative and diverse environment

  • Exceptional written, verbal communication and record keeping skills (with strong attention to detail)

  • Computer and data processing skills (Microsoft Office)

  • Preferred experience with molecular biology techniques including RNA/DNA isolation and restriction digestion, agarose gel electrophoresis, RT-PCR, qPCR, and DNA sequence analysis

Benefits:

The company offers competitive benefits including Medical, Dental, Vision, Short/Long Term Disability and Life Insurance, as well as 401(k) Match, Stock Options, Bonus, and Paid Leave Time. 

Additional Information:

  • All new hires are required to go through background and reference checks

  • OmniAb is an EEO/AA/Disability/Vets employer

  • Must be legally authorized to work in the US without sponsorship

  • OmniAb celebrates the diversity of life and welcomes all individuals to apply

  • New hires based in the US will be required to demonstrate that they have been fully vaccinated and boosted for COVID-19 or qualify for a medical or religious exemption or accommodation to this vaccination requirement

Base Pay Range:  $55,000 - $70,000/year

The pay range provided is an estimated base range for this role. Exact compensation may vary based on skills, experience, education, and location. We also offer an excellent benefits program which includes a selection of Medical and Dental plans, and Life, AD&D and Short-Term Disability insurance, Tuition Reimbursement, 401(k) with immediate Company match vesting, Company paid holidays and more!

OmniAb, Inc. is an Equal Opportunity Employer and does not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class.


Company

OmniAb, Inc.’s discovery platform provides pharmaceutical industry partners access to diverse antibody repertoires and high-throughput screening technologies to enable discovery of next-generation therapeutics. At the heart of the OmniAb platform is the Biological Intelligence™ (BI) of our proprietary transgenic animals, including OmniRat®, OmniChicken® and OmniMouse® that have been genetically modified to generate antibodies with human sequences to facilitate development of human therapeutic candidates. OmniFlic® (transgenic rat) and OmniClic® (transgenic chicken) address industry needs for bispecific antibody applications though a common light chain approach, and OmniTaur™ features unique structural attributes of cow antibodies for complex targets.

We believe the OmniAb animals comprise the most diverse host systems available in the industry and they are optimally leveraged through computational antigen design and immunization methods, paired with high-throughput single B cell phenotypic screening and mining of next-generation sequencing datasets with custom algorithms to identify fully human antibodies with superior performance and developability characteristics.

An established core competency focused on ion channels and transporters further differentiates our technology and creates opportunities in emerging target classes. OmniAb antibodies have been leveraged across modalities, including bispecific antibodies, antibody-drug conjugates and others.

The OmniAb suite of technologies span from BI-powered repertoire generation to cutting edge antibody discovery and optimization offering a highly efficient and customizable end-to-end solution for the growing discovery needs of the global pharmaceutical industry.

Find Us
Website
Location
5980 Horton Street
Suite 600
Emeryville
CA
94608
US

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