Research Associate II, Process Development

Who is BlueRock?
BlueRock Therapeutics, a wholly-owned and independently operated subsidiary of Bayer AG, is a leading engineered cell therapy company using its unique cell+gene platform to direct cellular differentiation and genetically engineer cells to create a new generation of cellular medicines that address large patient populations suffering from neurological, cardiovascular, and immunology diseases.The convergence of cell biology and genetic engineering is creating fundamental new ways to impact disease. Founded in 2016 to capitalize on these technological breakthroughs, we are advancing our novel cell+gene platform to develop, manufacture, and deliver an entirely new generation of authentic and engineered cell therapies across three therapeutic areas: neurology, cardiology, and immunology.
What Are We Doing?
Our foundational science harnesses the ability to create and then direct the differentiation of universal pluripotent stem cells into authentic, functional cells that can be used as allogeneic cellular therapies to treat a broad array of diseases. We can also further engineer these cells, enabling them to produce enzymes, antibodies, and other proteins for additional therapeutic benefit. We are passionate about delivering on the promise of cellular and gene therapy, shaping the future of cellular medicine, and delivering new therapies to millions of patients with treatment options. We are seeking individuals who are collaborative, thrive in a fun and dynamic culture, and are steadfast in the commitment to advance cutting-edge cellular therapies to impact patients’ lives.
BlueRock Therapeutics is seeking a Research Associate I or II, Process Development to join our team in Cambridge, MA. If you’re looking for a unique and diverse role encompassing several elements of the manufacturing process, look no further! From process development and analytics through to clinical manufacturing, this role covers a broad scope and involvement in the process from end-to-end. This position will collaborate with the team to develop, scale up the end-to-end manufacturing process and produce the clinical supply of authentic and engineered cellular products. With exciting pipelines and tremendous potential, this is an opportunity for a talented and self-motivated scientist to contribute to bringing cutting-edge cellular therapies to patients while gaining valuable career experience in Process Development.  Responsibilities:

 Support the development, optimization, scale up and tech transfer of the iPSC upstream and downstream manufacturing processes for authentic and engineered cellular products.

Participate in coordinated experimental planning and execution among team members and across functional teams.

Participate in supporting CMC/IND related activities, including but not limited to protocol driven studies to support process change, premanufacture pilot production and method qualification.

A background in in vitro experiments for differentiation, characterization and cultivation of pluripotent stem cells and derivatives is a plus.

Analyze, visualize, and document experimental data in electronic laboratory notebooks in a timely and accurate manner.

Prepare and follow standard operating procedures, batch records, reports, and other documentation.

Organize and present scientific data to peers at internal platforms.

This position requires occasional work on the weekend and after hours.

Minimum Requirements:

Minimum of a Bachelors (with 2-5 years of full-time lab experience) or Masters (with 0-3 years experience) in the life sciences, biomedical engineering, chemical engineering, biological sciences, molecular & cell biology or related fields is required.

Biotechnology or pharmaceutical industry experience is preferred.

Extensive experience in adherent and suspension mammalian cell culture is required.

Familiarity with cell characterization methods and technologies, such as flow cytometry, qPCR, immunoassays, and microscopy is preferred.

Hands-on experience with bioreactors and cell processing technologies is preferred.

Demonstrated ability to plan experiments and execute complex tasks is required.

Practical knowledge of experimental design (e.g., DoE) and statistical data analysis is preferred.

Strong written and verbal communication skills, and proficiency in technical scientific writing are required.

Excellent organizational skills are required.

Able to work independently and as part of a team in a fast-paced environment. 

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BlueRock Therapeutics Company Culture HighlightsWinner of Comparably's Award for Best Company for Diversity 2022Winner of Comparably's Award for Best Company for Women 2022Winner of Comparably's Award for Best CEO 2022BlueRock Therapeutics is ranked in the top 5% of companies for Overall Culture on Comparably.Engineering Department is ranked in the top 5% of companies for Overall Culture on Comparably.
Check us out on Comparably: https://www.comparably.com/companies/bluerock-therapeutics
Equal Opportunity Workplace: At BlueRock, we welcome and support differences and diversity and we are proud to be an equal opportunity workplace.  Please let us know if you require disability-related accommodation or other grounds protected by human rights legislation during the recruitment process so that we can work with you to meet your needs.