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Therapeutic Discovery Scientist - Protein/Antibody

Employer
Ascent Services Group
Location
94080, South San Francisco
Start date
Mar 15, 2023

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Discipline
Science/R&D, Biology, Biotechnology, Research, Molecular Biology
Required Education
Bachelors Degree
Position Type
Full time
  • MUST HAVES:
  • molecular bio exp and degree helpful NGS sequencing

Job Description:

  • Design and construct antibody libraries
  • Design, execute and manage antibody discovery campaigns
  • Lead and execute antibody discovery selections through phage and yeast display
  • Lead and execute antibody screening and characterization through methods such as ELISA, binding kinetics by SPR, flow cytometry and cell-based assays
  • Molecular cloning of library sequences for recombinant expression
  • Explore and implement new technologies in antibody engineering
  • Work in a matrixed team environment, routinely collaborating with Protein Science and Biology groups to advance programs

Required Qualifications:

  • BS degree or equivalent or equivalent industry experience
  • Experience with phage and/or yeast-display
  • Experience in designing and generating libraries such as site saturation and combinatorial variant libraries for protein optimization
  • Experience with structural and sequence analysis tools to guide the design of drug candidates
  • Experience in molecular biology including in techniques for DNA construction such as Gibson Assembly
  • Able to manage high throughput scientific workflows
  • Ability to work independently to design, execute, interpret, and troubleshoot experiments
  • Highly organized, experience with ELN documentation.
  • A team player with excellent verbal and written communication skills, ability to thrive in a fast-paced environment among a growing team

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