Therapeutic Discovery Scientist - Protein/Antibody
- Employer
- Ascent Services Group
- Location
- 94080, South San Francisco
- Start date
- Mar 15, 2023
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- Discipline
- Science/R&D, Biology, Biotechnology, Research, Molecular Biology
- Required Education
- Bachelors Degree
- Position Type
- Full time
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- MUST HAVES:
- molecular bio exp and degree helpful NGS sequencing
Job Description:
- Design and construct antibody libraries
- Design, execute and manage antibody discovery campaigns
- Lead and execute antibody discovery selections through phage and yeast display
- Lead and execute antibody screening and characterization through methods such as ELISA, binding kinetics by SPR, flow cytometry and cell-based assays
- Molecular cloning of library sequences for recombinant expression
- Explore and implement new technologies in antibody engineering
- Work in a matrixed team environment, routinely collaborating with Protein Science and Biology groups to advance programs
Required Qualifications:
- BS degree or equivalent or equivalent industry experience
- Experience with phage and/or yeast-display
- Experience in designing and generating libraries such as site saturation and combinatorial variant libraries for protein optimization
- Experience with structural and sequence analysis tools to guide the design of drug candidates
- Experience in molecular biology including in techniques for DNA construction such as Gibson Assembly
- Able to manage high throughput scientific workflows
- Ability to work independently to design, execute, interpret, and troubleshoot experiments
- Highly organized, experience with ELN documentation.
- A team player with excellent verbal and written communication skills, ability to thrive in a fast-paced environment among a growing team
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