Scientist - Automation and Screening

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

As a member of the Lilly Biologics Screening Group and Automation Team, the focus of the successful candidate will be to support research teams across multiple therapeutic areas by miniaturizing, adapting and executing assays to screen biologics using state-of-the-art lab automation.  The successful candidate will thrive in a fast-paced, highly collaborative environment in which they work synergistically and creatively with local colleagues and multiple project teams across the organization. 

Key Objectives/Deliverables:

• The candidate will be responsible for the execution and migration of manual recombinant protein and cell-based assays to automated instrumentation in 96/384-well formats.

• The successful candidate will independently create, troubleshoot and validate automated methods on liquid handling systems/workstations.

• The successful candidate will engage in the identification and evaluation of novel procedures or technologies that could serve to bolster the productivity of the antibody discovery and protein engineering teams.

• The candidate will analyze data sets and generate data reports for downstream users.

Basic Qualifications:

• B.S or M.S. in biology, biotechnology, biochemistry, molecular biology, or a related field with 3+ years relevant research experience in assay development & execution, preferably in drug discovery.

Additional Qualifications:

• Proficient in assay development, optimization and troubleshooting of plate based/cell-based assays in 96/384W format.

• Demonstrated expertise in diverse assay methods and technologies, such as reporter bioassays, ELISA, FRET/BRET, Alpha-ELISA and co-culture assays.

• Solid skills in cell culture techniques and working knowledge of cellular signaling.

• Experience working on an automated platform in a screening group is preferred.

• Demonstrated ability to use multiple software platforms for plotting and statistical analysis of large experimental data sets (e.g., TIBCO Spotfire, Graphpad Prism, Genedata Screener) is preferred.

• Demonstrated ability to successfully take on challenges and quickly adapt to new responsibilities.

• Detail-oriented and highly organized with the ability to run and prioritize multiple projects to meet timelines.

• Excellent written and oral communication skills, with a demonstrated ability to work in a highly collaborative team environment.

• Highly motivated with ability to work and think independently, research the literature, and master new skills, methods and technologies that enhance departmental capabilities.

Additional Information:

• Location: San Diego, California

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