Manager, Lab Operations

About Maze Therapeutics 

Maze is a clinical-stage biopharmaceutical company harnessing the power of human genetics to transform the lives of patients through the development of a pipeline of novel precision medicines for patients with genetically defined diseases. Maze is leveraging Compass™, a proprietary, end-to-end purpose built platform to advance a pipeline of precision medicines across four disease areas - renal, cardiac, neurological and metabolic diseases. Our flexible business model aims to translate our genetic insights into new therapies for patients as possible. 

Our People 

Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.  

Our Core Values 

Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission.   

Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.  

Stand True – Our integrity is foundational; it guides us no matter the obstacle.  

 Role Description: 

• Lead Laboratory Operations in a multidisciplinary BSL2 environment by organizing and supporting all aspects of daily operations and safety of the wet lab space
• Establish relationships with external vendors and create efficient procurement and inventory practices by identifying key consumables and reagents with research personnel
• Establish SOPs and manage shipping & receiving of lab supplies, equipment and reagents. Work with R&D team to ensure appropriate storage, documentation, and processing of samples
• Monitor and maintain laboratory equipment, schedule routine repairs/calibrations, and manage service contract renewals and software/hardware upgrades. Provide training on equipment as needed
• Manage/upgrade electronic inventory databases for chemical and biological reagents working with the research informatics and research teams. Ensure inventory management systems meet end-user requirements and are scalable to growing needs
• Plan and co-ordinate large-scale facility changes including lab reorganizations and/or expansion
• Serve as the primary point of contact with EH&S services and work closely in collaboration with the facility operations teams to maintain a safe, compliant, and fully-functional work environment
• Maintain overall lab organization and cleanliness, including lab design and layout for maximum workflow efficiency
• As head of the safety committee, you will establish lab procedures; create and manage lab-related documentation, and organizational processes such as annual laboratory cleanouts and micropipette calibrations 
• Work with Finance and Research Leadership teams to establish the lab operating budget and contribute to CapEx strategy and execution
• Anticipate, troubleshoot, and resolve problems associated with work within the laboratory setting, including occasional off-hours responses to laboratory emergencies
• Oversee the handling and disposal of hazardous and medical waste as per local government guidelines  

 Qualifications: 

• BS or higher degree in life sciences with 5+ years’ experience in lab operations, preferably in industry environment 
• Demonstrated in-depth experience establishing and managing lab set-up and ongoing operations
• Hands on knowledge in lab and workstation design, set up and relocation 
• Experience relocating lab equipment, chemicals, biologics, radiation, vivarium, and temperature sensitive samples and reagents 
• Up to date thorough understanding with local, state and federal government bodies that mandate lab safety and EH&S policies. Experience with leading the organizations safety committee is a plus
• Excellent analytical and flexible skills to understand complex lab issues and provide solutions with tight deadlines 
• Experience with CRO’s is a plus; experience in implementing and maintain data systems is a plus 
• Outstanding written and verbal communication skills with a team-oriented attitude  

The expected salary range for this role for employees located in the San Francisco bay area is $125,100 - $141,250. Additionally, this position is eligible for an annual performance bonus. 

Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills and job location. The expected salary range for this role may be modified in the future. 

Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.