Scientist, Stromal Biology Translational Research
- Bristol Myers Squibb Company
- Redwood City, California
- Start date
- Mar 10, 2023
- Regulatory, Science/R&D, Biology, Biotechnology
- Required Education
- Bachelors Degree
- Position Type
- Full time
- Biotech Bay, Best Places to Work
Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us
When you join BMS, you are joining a diverse, high-achieving team united by a common mission.
The Tumor Microenvironment Thematic Research Center (TME TRC) is focused on developing therapeutic targets at the intersection of tumor, stromal and immune biology within the TME with the goal of enhancing responsiveness to checkpoint blockade and targeted therapies and transforming response and durability rates for cancer patients. Comprising of scientists across multiple disciplines we are responsible for the biology and translational science necessary to support drug development from target identification through to first in human studies.
The Scientist will join the Immuno-Oncology and Stromal Biomarkers Translational Research team at Bristol Myers Squibb in Redwood City, CA to execute on translational research plans and develop prototype biomarker assays for immune and stromal targets within the tumor microenvironment. The qualified candidate is a highly motivated, interactive, and organized individual that possesses the ability to work across a matrixed environment to support progression of therapeutic targets and is interested in growth as a scientist. This position will specifically support the identification of potential predictive and pharmacodynamic biomarkers for therapeutic programs by characterizing primary human samples and employing them in functional assays. The candidate will also have the opportunity to develop prototype assays for receptor occupancy and target engagement to support clinical development. Finally, the candidate is expected to effectively collaborate with colleagues in the immunology, stroma, oncology, chemistry, and protein engineering groups through clear verbal and written communication skills.
In the role as a Scientist within TME TRC Translational Research, I-O & Stromal Biomarkers, the ideal candidate:
Applies scientific, technical skills, and functional knowledge to independently plan and select appropriate methodologies for translational research studies
Executes experiments to support indication prioritization and development of predictive and pharmacodynamic biomarker strategies, as well as assay development for therapeutic programs
Explores combination activity with standard-of-care agents with clinical candidates to support development strategy
Identifies and potentially develops new technologies and assays relevant for biomarker discovery and analysis
Documents and reports research findings
Makes presentations in multidisciplinary meetings, logically presenting information to convey clear, key messages
Actively participates in internal and external scientific meetings through presentations and critical evaluation of both internal results and emerging scientific literature
Collaborates effectively across different functions
May make decisions that impact entire workgroup/project team
5+ years of academic and / or industry experience
3+ years of academic and / or industry experience
Ph.D. or equivalent advanced degree in the Life Sciences
No experience necessary
Strong research experience in stromal biology and translational research
Strong knowledge of stromal biology, including fibroblast cells, extracellular matrix, and/or vasculature, in the context of cancer biology
Independence in experimental execution, data analysis, and troubleshooting =
Experience in handling primary cells, including cancer associated fibroblasts and immune cells from tumor tissues and peripheral blood
Experience performing functional assays, including co-culture assays to model the stromal-immune and cancer cell interactions in tumor tissues
Experience with multiple assay/technology platforms such as flow cytometry, ELISA (MSD, Luminex, etc), and genomic analysis (library prep, NanoString, qPCR, etc.)
Experience performing DNA, RNA, and protein isolation
Strong analytical skills and problem-solving/troubleshooting capabilities
Interprets own data, makes conclusions, and recommends next steps
Proficiency in utilizing software such as Graph Pad, Microsoft office etc. for data analysis and figure generation
Experience with prototype biomarker assay development
Some experience in bioinformatics and/or computational biology
Attention to detail with impeccable organizational and record keeping skills
Excellent interpersonal skills
Strong communication skills required, with an ability to communicate and translate ideas and data into concise written and verbal communication
The starting compensation for this job is a range from $97,000.00 – $135,300.00, plus incentive cash and stock opportunities (based on eligibility).
The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience.
For more on benefits, please visit our BMS Careers site.
Eligibility for specific benefits listed in our careers site may vary based on the job and location.
If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.
To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation.Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment.This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.
BMS is dedicated to ensuring that people with disabilities can perform complex functions through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, direct your inquiries to email@example.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
Bristol Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.
At Bristol Myers Squibb, we believe in the power of science to address some of the most challenging diseases of our time. Our focus on these unmet needs comes during a remarkable time, when unprecedented scientific breakthroughs are advancing the treatment of disease as never before in human history.
We work every day to transform patients’ lives through science. Each day, our employees around the world work together for patients – they are at the center of everything we do. They inspire us. They are the reason we come to work each day.
We combine the agility of a biotech with the reach and resources of an established pharmaceutical company to create a global leading biopharma company powered by talented individuals who drive scientific innovation.
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