Sr. Scientist, Gene Editing Innovation, Moderna Genomics

The Role:

As part of our vision, Moderna is committed to invest in R&D to further expand our impact on patients. We are building an independent research and business unit for genomic medicines, called Moderna Genomics (mGx) based in Technology Square, Cambridge, MA. mGx will be an innovation engine for the company focused on discovering and delivering the next generation of in vivo gene editing and nonviral gene therapies. It is our intention to be an industry leader in genomic medicines.

Moderna Genomics, Gene Editing Innovation (GEI) team seeks a curious and innovation-driven scientist with lab management experience to contribute to our initiatives to deliver the best-in-class gene-editing systems for precision therapeutics, leveraging our proven mRNA and delivery platforms. The candidate will have the unique role of driving both laboratory research and team management, working closely with GEI team leaders. The candidate will contribute to discovery research to characterize and engineer novel gene editing platforms, streamline existing protocols to establish SOPs for the GEI team. The candidate will engage in molecular biology, high-throughput assay development, and gene-editing experiments in mammalian cell and preclinical models, in collaboration with the broader mGx scientists. This role will have the opportunity to work at the cutting-edge of gene-editing space, make an impact through pioneering foundational protocols and experimental data using an array of molecular and cellular approaches.

This role will have the opportunity to make an impact by help building and managing a team with head of GEI to establish core functions, enabling the invention of new gene editing modalities that can be delivered safely to benefit an increased number of patients. You will be broadly involved in scientific discovery efforts within mGx. Further, as an early member of GEI, the successful candidate will be a key player in shaping and building the team and culture for this new initiative.

Heres What Youll Do:

• Help manage and streamline laboratory workflows and improve SOPs for discovery research

• Train new members of the team on basic assays spanning a range of biochemistry and molecular biology techniques, including gel electrophoresis, PCR, qPCR, NGS

• Apply experience in molecular biology, mammalian cell culture, high-throughput assays to carry out experiments with mRNA-encoded gene editors.

• Perform cell culture, including maintenance and manipulation of cell lines and primary cells

• Maintain clear and detailed research notebook

• Work well as part of a team

• Present findings to larger team and key stakeholders

Heres What Youll Bring to the Table:

• A PhD in Genetics, Cell or Molecular Biology, Synthetic Biology, or related field with 3+ years of post-graduate experience.

• Ability to learn quickly, adapt, and carry out controlled experiments through literature research

• Experience in mammalian cell culture, ideally with knowledge in high-throughput screening

• Hands-on experience in a variety of molecular and cellular biology techniques

• Excellent management and teamwork skills

• Previous experience with gene-editing technology is a plus

• Previous experience with NGS/genomics is a plus

• Excellent written and verbal communication skills

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

• Highly competitive and inclusive medical, dental and vision coverage options
• Flexible Spending Accounts for medical expenses and dependent care expenses
• Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
• Family care benefits, including subsidized back-up care options and on-demand tutoring
• Free premium access to fitness, nutrition, and mindfulness classes
• Exclusive preferred pricing on Peloton fitness equipment
• Adoption and family-planning benefits
• Dedicated care coordination support for our LGBTQ+ community
• Generous paid time off, including:
  Vacation, sick time and holidays
  Volunteer time to participate within your community
  Discretionary year-end shutdown
  Paid sabbatical after 5 years; every 3 years thereafter
• Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
• 401k match and Financial Planning tools
• Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
• Complimentary concierge service including home services research, travel booking, and entertainment requests
• Free parking or subsidized commuter passes
• Location-specific perks and extras!

Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible. Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.

About Moderna

In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit www.modernatx.com.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

-