Scientist II, Technology Development

The Role:

The Technology Development group at Life Edit discovers new genome editing systems and establishes new editing capabilities and optimizes them to support efforts developing curative gene editing therapies and gene edited cell therapies. We are looking for an enthusiastic, competent, and self-motivated Scientist with a strong background in mammalian cell culture and genome editing to help expand our technology development platforms and therapeutic capabilities.

Here’s What You’ll Do:

• Evaluate Life Edit gene editing systems in mammalian cells to identify optimal engineered systems for further therapeutic discovery and development
• Design, implement and troubleshoot experiments to improve Life Edit gene editing systems for a variety of therapeutic indications
• Develop assays to evaluate the effect of genotypic changes on disease specific functional endpoints
• Analyze experimental data and present scientific results at team research meetings
• Collaborate closely with computational biology, gene editing and preclinical teams

Requirements:

• Ph.D. in Biology, Biochemistry, Cell Biology, or a related field with 2+ years of experience
• Extensive expertise culturing, transfecting, and analyzing cell lines and primary cells, experience with hepatocytes is a plus  
• Direct experience delivering genome editing systems to mammalian cells using multiple delivery methods including nucleofection, lipofection, and lipid nanoparticles
• Experience with modern molecular biology techniques including DNA/RNA extraction, PCR, qPCR, NGS, Flow cytometry and ELISAs
• Experience with laboratory automation and liquid handlers is a plus
• Experience maintaining and organizing ELN documentation
• Demonstrated ability to work independently and collaborate in a team-oriented environment
• Outstanding written and verbal communication skills
• Industry experience strongly preferred

We’re committed to finding the best ways to support our teams so they can do their best work. We take care of our employees, right from the start.

Health & Wellness

• Medical, vision, and dental insurance covered at 90%
• Low deductible, no co-insurance and no copays for mental health visits (for in-network care)
• Annual fitness reimbursement
• Employer paid for access to wellness apps and programs like Task Human

Financial

• Competitive compensation
• 401(k) retirement plans with a 4% employer match and no vesting period
• Employer-paid life insurance and short- and long-term disability insurance
• Employer-sponsored flexible spending accounts (FSA) and dependent care account (DCA)
• Access to a 1-on-1 financial advisor
• Commuter reimbursement benefit
• Monthly cell phone stipend

Time Off & Flexibility

• Unlimited paid time off, including vacation, sick leave, family leave, personal days, and bereavement
• 18 paid company holidays, plus an end-of-year holiday shut down
• 12 weeks of parental leave
• Federal Family and Medical Leave Act (FMLA) and Massachusetts Paid Family and Medical Leave (PFML), administered by Unum

Development Journey

• Insights Discovery training for every employee to make the most of workplace relationships
• Ongoing professional development, including manager training
• Access to LinkedIn Learning, a self-guided online education platform

Why join Life Edit Therapeutics?

Life Edit Therapeutics, an ElevateBio portfolio company, is a gene editing company on a mission to rewrite the future by curing disease, making any edit, anywhere. Life Edit has built a world-class genome editing platform with one of the world’s largest and most diverse collections of novel RNA-guided nucleases (RGNs) and base editors. The company’s next-generation editing systems will propel the development of novel human therapeutics by enabling ex vivo engineering for cell therapies and regenerative medicines and in vivo delivery of gene therapies.

Our Vision:  To pave the way to faster, safer, gene editing therapeutics that cure disease and improve patient lives

Life Edit is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Life Edit will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.