Associate Scientist - Inflammation
United States - California - Foster City
Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.Making an impact on a global scale
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Gilead Sciences (Foster City, CA) is seeking a talented and highly motivated Associate Scientist to join our Inflammation group. Our collaborative and interdisciplinary research team utilizes state-of-the-art technologies and innovative methodologies to advance medicines into the clinic. The successful candidate is expected to be lab-based and to contribute to the discovery, research, and development of novel immunotherapeutic agents to address unmet medical needs of inflammatory diseases including inflammatory bowel disease. He/she/they will support projects across discovery research and into early development on multidisciplinary project teams. The successful candidate will participate as an engaged member of a collaborative department with diverse research interests. He/she/they will also independently design and execute experiments to advance our understanding of disease biology. The candidate will have opportunities for career growth through acquisition of new skills, experiences, and professional relationships in a fast-paced and resource-rich environment.
Our values - integrity, inclusion, teamwork, accountability and excellence - are evident in everything we do.Essential Functions:
The successful candidate will support pre-clinical development and discovery efforts of novel therapeutics for inflammation targets, including the development and execution of proof of concept and validation assays.
The candidate will also drive immunological studies assessing the mechanism of action of pre-clinical and clinical Gilead compounds.
They will support projects from discovery research into early development as an active member of cross-functional teams and support translational efforts in the inflammation space.Knowledge, Experience and Skills:
The candidate must have a background in immunology, cellular and molecular biology, or related field.
The candidate must be driven, able to work independently with minimal supervision, and display scientific rigor and technical excellence. Excellent organizational skills in management of data, and experimental protocols are essential.
The candidate will participate in regular team meetings and present results, interpretation of data, and formulate conclusions. Teamwork and excellent verbal and written communication skills are critical. Qualifications and requirements:
-Degree in immunology, cell and molecular biology, or related biological science.
-BS with 6+ years or MS with 4+ years of relevant post-graduate research experience or drug development experience in immunology, cell biology, molecular biology or related filed.
-Team-oriented, enthusiastic, and flexible
-Proficient in cell culture techniques: culturing cell lines and isolation of primary cells, cell engineering (transfection, transduction, etc)
-Proficient in RNA isolation and qPCR
-Strong background and hands-on experience in immunology, inflammatory diseases, or immune modulation strategies preferred.
-Demonstrates proficiency and drive to perform wet lab immunology techniques, including development and implementation of in-vitro cell based functional assays, transfection / transduction of primary cells and cell lines, flow cytometry, ELISA, Luminex/MSD assays, and other immunoassays.Preferred Qualifications:
Preference will be given to candidates with industry experience in immunology or intestinal/mucosal biology.
Additional laboratory skills preferred: molecular biology, tissue processing, qPCR, microscopy, 3-D organoid culture.
In vivo experience with mouse disease models is preferred.
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