Sr Research Scientist II, Research Data Sciences - Protein Therapeutics

Sr Research Scientist II, Research Data Sciences - Protein Therapeutics
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company’s five core values. That’s because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

At Gilead we believe every employee deserves a great leader. As a people leader now or in the future, we expect that you will model and create an environment of inclusion, be intentionally focused on the hiring, development, growth and retention of talent, and empower teams to align and achieve goals.
Job Description


We are seeking a motivated data scientist with experience in biologics to take a lead role in building out data science capabilities to enable Protein Therapeutics objectives. The position provides a unique opportunity to work closely with highly diverse and collaborative groups of computational and wet-lab scientists, apply state-of-the-art data science methodologies and implement scalable analytical solutions to the design, discovery, engineering, and characterization of antibody-based therapeutics.

The successful candidate will work closely with Protein Therapeutics scientists to design experiments, build datasets, adopt machine learning and statistical modeling methods, and implement computational tools to enable the discovery and engineering of biologics. The individual will collaborate cross-functionally and contribute to establishing systems and practices for efficient and scalable high throughput data capture, integration, and the generation of predictive models. The individual will play a key role in therapeutics project teams, analyzing diverse multidimensional data to inform teams to make data-driven decisions. The individual can also initiate/lead collaborations and research efforts for novel method development and drug discovery.

Essential Functions:

• Develop computational analysis pipelines to analyze antibody sequences from in vivo and in vitro selections

• Develop statistical designs and machine learning models for biologics to advance protein therapeutics programs
• Develop and apply analytical methods for antibody/protein design and developability engineering, utilizing large-scale NGS and other in-house and external data sources
• Develop computational methods and implement interactive data visualization solutions to enable experimental multi-variate analysis and data-driven decision-making
• Work side-by-side with scientists across PT functions to capture, aggregate, and visualize structured data to generate meaningful metrics and testable hypotheses
• Collaborate cross-functionally with informatics and IT colleagues to evaluate and establish scalable and structured data science capabilities for Protein Therapeutics
• Provide technical expertise and data science leadership in protein therapeutics project teams
• Author and contribute to presentations, publications, and patents

Knowledge, Experience and Skills:

• Expertise in developing algorithms and applications for predictive modeling, pattern recognition, data mining and visualization of large-scale datasets.
• Experienced in bioinformatics analysis and mining of large-scale antibody sequences
• Knowledgeable and experienced in protein science and antibody discovery and engineering
• A proactive and self-motivated individual with a strong work ethic and scientific rigor, ability to work in a dynamic environment and manage multiple objectives in parallel and adapt to changing priorities
• Excellent interpersonal and communication skills to drive strategic solutions.
• Innovative and collaborative with an entrepreneur mindset to thrive in a diverse and multidisciplinary environment

Required Qualifications:

• A PhD in Computational Biology, Biostatistics, Computer Science, or a related discipline with demonstrated expertise in biologics and data science, with a minimum of 5 years of relevant work experience or MS with 10+ years of relevant experience. Industry experience is preferred.
• Proficiency in R, Python, or C/C++ programming languages, shell scripting and command line tools
• Proficiency in Linux environment, HPC and cloud computing

For jobs in the United States:

As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@gilead.com for assistance.

Following extensive monitoring, research, consideration of business implications and advice from internal and external experts, Gilead has made the decision to require all U.S., Canada, Australia, Singapore, and Hong Kong employees and contractors to receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.​

For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.

NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT

PAY TRANSPARENCY NONDISCRIMINATION PROVISION

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.






jeid-0f93ecb598cced4bb98bc51f0745b0e9