Scientist, Cell Product Characterization

About the role

Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who want to challenge the status quo, and who lead with the desire to work on novel ideas. We are looking for a creative Scientist to join our Product Characterization team in Analytical Development Department. You will report to the Director of Cell Product Characterization to establish potency strategies of gene-edited cell products. You will assume a role in developing assays and strategies to support functional characterization and potency for T cells drug product and others. You will work with a multi-function team to deliver gene-edited T cells for clinical use.

What you'll do

• Complete essential experimental studies on testing CAR-T cell potency for T cell polyfunctionality characterization
• Work with other groups such as Research and Process Development to produce data and support process development, formulation studies, stability studies, and potency of drug product
• Design and complete important experimental studies on testing gene-editing materials (mRNA, sgRNA etc) activities
• Document all experimental work, supporting data in an electronic lab notebook (ELN) promptly
• Participate in crucial conversations and collaboration

What we're looking for

• Ph.D. in Immunology, Cell Biology +2 years of academic/industry experience or BA/MS +7 years academic/industry experience
• Direct experience performing potency and functional assay development such as Flow Cytometry, cell-based functional assay and ddPCR
• Proficiency in mammalian cell culture and assay development
• Ability to present to teams with diverse backgrounds
• Collaborator with an agile mindset to excel in a team-oriented organization

What will separate you from the crowd

• Familiarity with cell therapy analytics and cell sorting
• Working knowledge of CMC and interpretation of FDA/EMA and ICH guidelines
• Ability quickly to assess and implement new technologies

What you should know

• Ability to work in BSL-1 and BSL-2 labs
• Prolonged standing and sitting
• Manual dexterity required to operate office and lab equipment
• Occasional weekend work
• Occasional travel to other Sana locations
• Working safely in person on a predictable and regular basis is an essential job function for this position, and the Company requires that all individuals working in-person be fully vaccinated against COVID-19
• The base pay range for this position at commencement of employment is expected to be between $130,000 and $160,000/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience

How we work together

• Lead from every seat – we seek to understand, act with honesty, and engage in the crucial conversations
• Thrive as a team – we hire amazing people, are intensely curious, and cultivate inclusion and personal connectivity
• Make it happen – we value vigorous debate, alignment around our decisions, and resilient execution 

Get to know us

At Sana, we believe that a diverse workforce strengthens us as a company and helps us to achieve our mission to meaningfully change the outcome of many human diseases. This belief is a pillar of our business and is critical to our success. Our goal is that Sana is the place for talented people to bring their authentic selves to work, to have a great career and to deeply, positively impact patients.

Core to our values, we believe there is nothing more important than the health and wellness of you and your family. For benefit eligible employees, we cover 100% of the cost for employee health coverage and offer generous time-off (various paid time off benefits, such as holidays, vacation, sick time, and parental leave), short- and long-term disability, employer paid basic life insurance, additional voluntary life insurance protection, financial wellness programs including financial planning resources, a 401(k) Plan with an immediately vested employer match, Tuition Reimbursement and Student Loan Repayment, Employee Stock Purchase Plan, commuter subsidy and a variety of wellness offerings to support each person individually.  For more details on our benefits, visit Sana’s Benefits Portal.

We are committed to providing a workplace free of discrimination and harassment based on race, color, religion, age, gender, national origin, ancestry, physical or mental or sensory disability (including the use of a trained guide dog or service animal by a person with a disability), genetic information, actual or perceived HIV or Hepatitis C infection, medical condition (cancer or a record or history of cancer and genetic characteristics), marital status, sexual orientation, sexual preference, pregnancy (including childbirth and related medical conditions), disability, veteran status, political ideology, social class (including caste/caste identity), taking or requesting statutorily protected leave, status as a victim of domestic violence, sexual assault or stalking, or any other basis prohibited by applicable law.

To perform this job successfully, you must be able to perform each job responsibility satisfactorily. The job description listed above is representative of the knowledge, skills, and/or abilities required for this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the functions described above.