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Research Associate/Scientist, Analytical Development

San Diego, CA
Start date
Mar 3, 2023

Job Details

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Job Description

Research Associate/Scientist

Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Research Associate/Scientist in our Analytical Development department at our San Diego, CA location.

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Here, you will be a vital contributor to our inspiring, bold mission.


  • Provide theoretical/conceptual input to the design, development, implementation of novel analytical methods to support research projects relating to the development of antisense or siRNA oligonucleotide-based therapeutics.
  • Contribute to multiple projects, generating and analyzing complex data independently to help guide project direction and decisions.
  • Communicate findings to manager/department/project teams and proactively offer ideas for troubleshooting and/or next steps for potential resolutions.
  • Represent line function on cross functional Pharm Sci. teams as appropriate/necessary.


  • Independently develop and implement analytical methods to quantitate and characterize proprietary ASO and siRNA based therapeutics and conjugates thereof, such as GalNAc, antibody, peptide, lipid, small molecule, and siRNA encapsulated in LNPs.
  • Understand project timelines and deliverables and plans/coordinate project work accordingly with departmental, functional, and external stakeholders.
  • Perform complex research lab assignments independently.
  • Prepare and present technical information at team meetings.
  • Assist in development of innovative high-resolution mass spectrometry-based identification and quantification platforms.
  • Hands-on experience with various analytical methods such as LC, LC-MS/MS, etc. to support analysis of oligonucleotides.
  • Troubleshoot non-routine methods, instrumentation, or software issues and recommend systems, processes, or changes within project scope to meet objectives.
  • Utilize literature search to increase knowledge base and implement improvements such as to identify emerging trends in oligonucleotide and oligo-conjugate analysis and maintain awareness of new state-of-the-art techniques.
  • Work cross functionally to build internal capabilities.
  • Participate in external interactions and collaborations to support method development, transfer, and analysis of oligonucleotides.
  • Serve as a technical resource for junior staff and leverages expertise in laboratory technology as a functional resource/trainer


  • Analytical and Problem-Solving Skills - Able to troubleshoot critical issues or problems, and determine causes and possible solutions
  • Teamwork - Ability to work well in highly cross functional team environment and across global line functions
  • Communication Skills -Able to express one’s self clearly and concisely within team; document issues and/or concerns concisely with colleagues; adjust communication style as appropriate for the audience; timely and effectively communicate issues to supervisor; technical writing skills to support authorship of internal technical documents
  • Organization - Exercise good time management and prioritization skills and is able to successfully manage multiple tasks simultaneously
  • Knowledge Sharing - Ability to capture organizational knowledge; improve solutions, processes, and deliverables through use of information; improve information capital by contributing experience, theories, deliverables, and models for others to use
  • Resource Management -Ability to manage one’s time within individual, departmental, and corporate goals, and timelines; management of internal and external resources (vendors)
  • Technical - Proven track record of scientific contributions in the development of oligonucleotide analytical methods to support oligonucleotide delivery platform development. Biotech and pharma experience. Maintain understanding of current standards and practices for oligo bioanalysis which may be supported through intermittent trainings, conferences, and literature
  • PhD degree in chemistry, biology, pharmacy, engineering, or related pharmaceutical science with 0+ years relevant experience, or
  • MS degree in chemistry, biology, pharmacy, engineering, or related pharmaceutical science with 6+ years relevant experience, or
  • BS degree in chemistry, biology, pharmacy, engineering, or related pharmaceutical science with 8+ years relevant experience
  • Demonstrated involvement in professional community evidenced by presentation of scientific posters or lectures at professional conferences or events

Base Salary Range: $102,000-$146,000, based on candidate professional experience level. Employees may also be eligible for Short Term and Long-Term Incentive benefits as well. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off.

In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.


  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days
  • Community Outreach Programs

Empowering Our People to Shine

Discover more at

No Phone Calls or Recruiters Please.


EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.


San Diego, CA

Worker Type


Worker Sub-Type


Time Type

Full time


Takeda is a global, values-based, R&D-driven biopharmaceutical leader headquartered in Japan, committed to discover and deliver life-transforming treatments, guided by our commitment to patients, our people and the planet. Takeda focuses its R&D efforts on four therapeutic areas: Oncology, Rare Genetics and Hematology, Neuroscience, and Gastroenterology (GI). We also make targeted R&D investments in Plasma-Derived Therapies and Vaccines. We are focusing on developing highly innovative medicines that contribute to making a difference in people’s lives by advancing the frontier of new treatment options and leveraging our enhanced collaborative R&D engine and capabilities to create a robust, modality-diverse pipeline. Our employees are committed to improving quality of life for patients and to working with our partners in health care in approximately 80 countries and regions.

For more information, visit

Stock Symbol: TAK

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650 East Kendall Street
United States

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