Executive Director, Quantitative Biology, Moderna Genomics

The Role:

The Executive Director, Quantitative Biology is a senior leadership position within Moderna Genomics (mGx), responsible for building and leading the quantitative biology organization. This leader will be relentless in unlocking the full potential of our platform technology to support gene editing drug discovery and development efforts. Leading a diverse team of computational scientists, the leader will apply cutting edge computational approaches and analysis strategies for omics data, as well as interpretation of clinical and biomedical applications within the gene editing and gene delivery space.The Executive Director, Quantitative Biology will envision and build the strategy, infrastructure, data capture, internal expertise and analytics necessary to realize the mission of Moderna Genomics to deliver personalized gene editing medicines to patients.

This leader is part of a growing community of practice that includes colleagues in our Digital, Translational, and Development organizations committed to applying advanced computational techniques to accelerate mRNA medicines at Moderna.

Heres What Youll Do:

• Define the Computational Science strategy for Moderna Genomics, applying deep domain expertise to conceptualize approaches and capabilities and set priorities to accelerate mGxs gene editing research and development

• Provide direct scientific leadership in the analysis of genomics datasets, analysis of transcriptomic, imaging and functional data to deliver biological insights, the mining of publicly available and proprietary genomics databases to make novel insights, the interpreting of results, the building of effective tools and the correlations of genomic/genetics data

• Identify high impact settings in which to leverage Quantitative Biology capabilities to accelerate development of our gene editing and functional genomics technology and lead the organization to execute against research plan and scientific deliverables with a sense of urgency

• Educate and enable Moderna Genomics teams to develop research plans and design, execute, and analyze experiments that best leverage computational approaches

• Become fluent in the biology, chemistry, and pharmacology that underlie our platform technology and mRNA based genomic medicines

• Establish new capabilities and implement new techniques and strategies as needed as the gene editing and functional genomics field advances and our needs evolve

• Establish strong working relationships with key stakeholders and collaborators within mGx the wider computational community and relevant cross-functional teams within Moderna.

• Deliver high-quality scientific presentations internally and externally to a variety of audiences, including leadership teams, governance committees, and scientific conferences

• Conceptualize and contribute to peer-reviewed research articles and patent applications

• Regularly assess external advances pertaining to Computational Science experimental and analytical techniques that could be implemented in the development of genomics medicines

• Maintain strong external presence, building partnerships with advisors, KOLs, etc.

Heres What Youll Bring to the Table:

• Ph.D. in a scientific field with 15+ years of direct experience in the fields of computational biology and/or bioinformatics.Experience or knowledge in gene editing or DNA repair is highly preferred.

• Track record of successful leadership, including training, developing, and managing talent.

• Proven ability to build, motivate and inspire high performing teams, as well as effectively collaborate with cross-functional teams.

• Demonstrated effective organizational skills, including ability to set, prioritize and achieve research goals.

• Strong coding abilities in R and Python, in-depth knowledge and experience in high throughput sequence data analysis, specifically with designing principles and state-of-the-art analysis approaches for whole genome, deep amplicon sequencing, and synthetic and natural libraries.

• Strong scientific background with a track record of demonstrated innovation and strong external scientific presence

• Experience with software development (version control, unit and integration testing, documentation, and deployment) and high-performance computing and cloud computing platforms

• Proficiency in building custom data visualization tools

• Great team player and ability to build strong working relationships with multiple senior stakeholders across the R&ED, Clinical Development, Digital, and Informatics functionalities within Moderna to identify areas of synergy, prioritize workstreams and ensure timely completion of work.

• Thrives in a fast-paced/results-oriented environment.

• Current presence or willing to relocate to Cambridge vicinity.

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

• Highly competitive and inclusive medical, dental and vision coverage options
• Flexible Spending Accounts for medical expenses and dependent care expenses
• Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
• Family care benefits, including subsidized back-up care options and on-demand tutoring
• Free premium access to fitness, nutrition, and mindfulness classes
• Exclusive preferred pricing on Peloton fitness equipment
• Adoption and family-planning benefits
• Dedicated care coordination support for our LGBTQ+ community
• Generous paid time off, including:
  Vacation, sick time and holidays
  Volunteer time to participate within your community
  Discretionary winter shut down
  Paid sabbatical after 5 years; every 3 years thereafter
• Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
• 401k match and Financial Planning tools
• Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
• Complimentary concierge service including home services research, travel booking, and entertainment requests
• Free parking or subsidized commuter passes
• Location-specific perks and extras!

Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible. Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.

About Moderna

In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit www.modernatx.com.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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