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Research Associate II, Vaccine Process Development

Cambridge, Massachusetts
Start date
Feb 24, 2023

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Job Details

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Job Description


Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Research Associate II-Vaccine Process Development in our Cambridge, MA office.

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to provide Better Health and a Brighter Future to people around the world.

Here, you will be a vital contributor to our inspiring, bold mission.


Execute laboratory studies in support of process development, process scale-up and process scale-down for the production of Taketa's vaccine candidates.

Produce cell culture media, solutions, and buffers in support of lab scale vaccine production. Passage mammalian cells and assist in cell culture scale-up.

Provide experience in down stream processing activities such as chromatography and ultra filtration Assist in preparing and analyzing vaccine production samples.

Prepare technical reports, summaries, protocols, and quantitative analyses of experimental procedures, when required.

Coordinate information exchange between functional groups within Takeda including Formulation Development, Analytical Development, Analytical Services and Discovery groups. Operate bioprocessing equipment such as bioreactors, ultrafiltration, and chromatography units.


Design and perform a wide variety of technical procedures and operate a wide variety of lab instrumentation/computer platforms with minimal supervision.

Effectively analyze and summarize experimental outcomes, record experimental procedures and raw and analyzed data

Write experimental protocols and laboratory SOPs Coordinate efforts between internal and external teams such as Analytical Development, Drug Product Development, Analytical Services, and Quality Assurance.

Develop methods to improve existing techniques and/or efficiencies


MS in Physical or Life Sciences or a BS in Physical or Life Sciences with a minimum of 2 years relevant experience.

Detailed knowledge of theoretical basis and objectives of experiments and how they fit into overall project goals

Knowledge and skills in microbial and/or animal cell culture and protein and/or virus purification required

Training and experience in laboratory scale process science including process scale-up and scale-down required

Maintain familiarity with current applicable scientific literature and contribute to the process of a project within her/his scientific discipline, as well as investigate, create, and develop new methods and techniques for project advancement.

Personal motivation to expand applicable scientific knowledge through reading and by attending seminars and research meetings.

Experience with cell culture techniques including manual cultivation of cells in small scale flasks and operation of stirred tank and/or packed bed bioreactors OR experience with purification techniques including cell harvest technologies, preparative chromatography and normal and tangential flow filtration techniques required.

Experience with single-use cell culture and/or purification technologies strongly desired Experience with analytical methods used in support of process development strongly desired Experience in down stream processing utilizing chromatography and ultrafiltration strongly desired

Working knowledge of Biologics cGMPs including ICH guidance documents strongly desired


Manual dexterity required to operate office equipment (i.e. computers, phones, etc.).

Typical office and laboratory bending, stooping, lifting requirements apply.

Lifting and moving supplies and equipment (up to 50 pounds).


Requires less than 15% travel

Location and Salary Information:

Base Salary Range: $64,000 to $91,000, based on candidate professional experience level. Employees may also be eligible for Short Term and Long-Term Incentive benefits as well. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off.

The final salary offered for this position may take into account a number of factors including, but not limited to, location, skills, education, and experience.

This position is currently classified as “hybrid” in accordance with Takeda’s Hybrid and Remote Work policy.”


  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement
  • Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days
  • Community Outreach Programs

Empowering Our People to Shine

Discover more at

No Phone Calls or Recruiters Please.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.


Cambridge, MA

Worker Type


Worker Sub-Type


Time Type

Full time


Takeda is a global, values-based, R&D-driven biopharmaceutical leader headquartered in Japan, committed to discover and deliver life-transforming treatments, guided by our commitment to patients, our people and the planet. Takeda focuses its R&D efforts on four therapeutic areas: Oncology, Rare Genetics and Hematology, Neuroscience, and Gastroenterology (GI). We also make targeted R&D investments in Plasma-Derived Therapies and Vaccines. We are focusing on developing highly innovative medicines that contribute to making a difference in people’s lives by advancing the frontier of new treatment options and leveraging our enhanced collaborative R&D engine and capabilities to create a robust, modality-diverse pipeline. Our employees are committed to improving quality of life for patients and to working with our partners in health care in approximately 80 countries and regions.

For more information, visit

Stock Symbol: TAK

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