Bioanalytical Chemist

Bioanalytical Chemist

Job ID: req3317
Employee Type: exempt full-time
Division: Cancer Research Technology Program
Facility: Frederick: ATRF
Location: 8560 Progress Dr, Frederick, MD 21701 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.  The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.

PROGRAM DESCRIPTION         

The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives.  The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community.  A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers. In addition, the CRTP hosts the Nanotechnology Characterization Laboratory (NCL) which performs and standardizes preclinical efficacy and toxicity testing of nanoparticles intended for cancer therapeutics and diagnostics, and the Antibody Characterization Lab (ACL) which characterizes monoclonal antibodies or other renewable affinity binding reagents for use in cancer related research.  CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise.

The Nanotechnology Characterization Lab (NCL) serves as a national resource and knowledge base for all cancer researchers to facilitate the regulatory review of nanotechnologies intended for cancer therapies and diagnostics.  By providing the critical infrastructure and characterization services to nanomaterial providers, the NCL accelerates the transition of basic nanoscale particles and devices into clinical applications.

KEY ROLES/RESPONSIBILITIES

• The Nanotechnology Characterization Lab (NCL) provides nanotechnology characterization services for universities and the pharmaceutical industry (http://ncl.cancer.gov). This position will provide bioanalytical support for NCL's pharmaceutical customers.

• He/she will assist in analytical characterization and development of new bioanalytical methods for evaluating nanomedicines.
• Responsibilities include preparation of biological samples from pharmacokinetic and drug metabolism studies, and analysis by mass spectrometry.

BASIC QUALIFICATIONS

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

• Bachelors degree from an accredited college and university according to the Council for Higher Education Accreditation (CHEA) in pharmaceutical science, chemistry, biochemistry, biology or related discipline. 
• Foreign degrees must be evaluated for US equivalency.
  
• In addition to the education requirement, minimum five (5) years related experience.
• Demonstrated background in analytical and/or bioanalytical chemistry
• Experience with preparation of biological samples for quantification of small molecule drugs, including methods, such as HPLC, LC-MS/MS, LLE, SPE.
• Experience analyzing, preparing, and summarizing analytical data.
• Ability to obtain and maintain a security clearance.

PREFERRED QUALIFICATIONS 

Candidates with these desired skills will be given preferential consideration:

• Familiarity with drug development and the pharmaceutical industry.
• Demonstrated analytical problem-solving skills.
• Ability to multi-task and work with a diverse research group.
• Excellent coordination and communication skills.
• Some knowledge of drug metabolism-pharmacokinetics (DMPK).
• Ability to work independently in a cross-disciplinary setting.

JOB HAZARDS

• This position is subject to working with or have potential for exposure to animal(s) and/or animal material(s).
• This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations.
• This position is subject to working with radioactive material and requires to become an approved radiation worker.

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)

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