Associate Scientific Director, Liver Disease

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Job Description

About the role:

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.

Join Takeda as an Associate Scientific Director where you will lead efforts focused on establishing the mechanism of action (MOA) of drug candidates for the treatment of chronic liver diseases. You will also design and implement MOA and biomarker-discovery projects in collaboration with internal research teams, external partners, and/or CROS and be a scientific thinker with a strong understanding of the molecular/cellular basis of liver fibrosis as evidenced by publications and/or drug development experience. As part of the Liver Disease Research team, you will report to the Head of Liver Disease Research and work with Gastroenterology Drug Discovery Unit (GI DDU) as a collaborative scientist, who acts as a senior scientific consultant to and/or leader of research and clinical-stage cross-functional project teams.

How you will contribute:

• Develop and oversee scientific projects and manage the work of others in a matrixed structure.
• Lead efforts to determine the mechanism of action and/or discovery of a translational biomarker for drug candidates using state-of-the-art methods and tools.
• Be the scientific leader and target champion on cross-functional drug development teams and provide technical leadership in areas of expertise.
• Support and/or identify BD opportunities that support specific projects and the overall liver portfolio development strategy.
• Prepare technical reports, summaries, and quantitative analyses.
• Be the scientific mentor and thought leader.
• Communicate with colleagues and senior management.

Minimum Requirements/Qualifications:

• Ph.D. degree in a scientific discipline with 7+ years of experience researching the molecular/cellular basis of complex diseases and/or molecular pharmacology of biologics, therapeutic antibodies, or oligonucleotide-based therapeutics.
• Experience with complex biological systems gained from studies of embryonic development, disease pathogenesis, or pre-clinical therapeutic mechanisms of action or biomarker discovery, with a preference for liver biology.
• Solve scientific problems using multiple, state-of-the-art technologies and approaches.
• Demonstrate exceptional project management skills and in-depth expertise in a scientific discipline.
• Expertise in the design and execution of in vivo studies for evaluating liver-related biology, NASH/fibrosis pathophysiology, and/or biomarker discovery in liver diseases.
• Knowledge of animal models of liver disease, NASH, and fibrosis.
• Expertise in one therapeutic modality or biomarker discovery (small molecules, antibodies, biologics, ASOs/siRNA) and familiarity with the other modalities.
• Requires approximately 15-20% or more travel, including international travel.

What Takeda can offer you:

• Comprehensive Healthcare: Medical, Dental, and Vision
• Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan
• Health & Wellness programs including onsite flu shots and health screenings
• Generous time off for vacation and the option to purchase additional vacation days
• Community Outreach Programs and a company match of charitable contributions
• Family Planning Support
• Flexible Work Paths
• Tuition reimbursement

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best-in-class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

This position is currently classified as "hybrid" in accordance with Takeda's Hybrid and Remote Work policy.

Base Salary Range: $143,500.00 to $205,000.00, based on the candidate's professional experience level. Employees may also be eligible for Short-Term and Long-Term Incentive benefits as well. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program, and Paid Volunteer Time Off.

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EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time