Sr. Scientist, Protein Biochemistry (AAV, LNP, gene therapy)

We are seeking a highly motivated Sr. Scientist to join the Protein Biochemistry group. We are responsible for performing a variety biochemical and biophysical assays to characterize protein biologics and gene therapy candidates to support late-stage development and commercialization efforts. The ideal candidate will be diligent, efficient, flexible, and able to perform key responsibilities in a fast-paced, team environment.

A day as a Sr. Scientist looks like:

• Conducts biochemical and biophysical characterization experiments on therapeutic protein and gene therapy candidates (AAV/pseudovirus) for late-stage development and regulatory submissions. 
• Provide input on experimental design and suggest modifications in protocols or experimental methods to meet the needs of a particular program or molecule. 
• Will take on additional responsibilities in method development to support efforts to enrich and characterize size/charge variants of therapeutic protein and gene therapy drug candidates.
• Documents experiments, results and findings in electronic laboratory notebook; presents work at group and department meetings; contributes to drafting of protocols, method development reports, regulatory submission sections, and peer-reviewed articles for publication.
• Maintain instruments, troubleshoot instrumental/experimental problems, and order/maintain supplies.

This role may be for you if you have:

• An in-depth knowledge about protein structure and function.
• Experience with developing new analytical method and optimizing existing methods is preferred.
• Experience with some of the following techniques is preferred: H/UPLC, light scattering and capillary electrophoresis.
• The desire and ability to work in a team environment.
• A passion for science and innovation with a strong dedication to continual improvement and making significant contributions in a collaborative environment.

In order to be considered, you must have a PhD in analytical chemistry, biophysics, biochemistry, pharmaceutical sciences, chemical engineering or equivalent with 0-5 years post-doctoral training. Or a BS+ 10 years or an MS + 8 years relevant expereince. This may be combined with industry experience in analytical characterization of proteins, ADCs and mRNAs. Experience with the following techaniques would be a plus: qPCR, ddPCR, NGS. Prior experience with AAV, pseudovius and LNP is a plus

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits including health and wellness programs, fitness centers and equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.

The salary ranges provided are shown in accordance with U.S. law and apply to U.S. based positions, where the hired candidate will be located in the U.S. If you are outside the U.S, please speak with your recruiter about salaries and benefits in your location.

Salary Range (annually)

$103,600.00 - $169,000.00