Co-op, Cell Therapy Process Development - Large Scale

Why Join Intellia?

Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.

Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.

We wantall ofour people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together.

How you will Achieve More with Intellia:

We are seeking a talented and motivated co-op to join our vibrant Cell Therapy Process Development Team. If you are interested in gaining real-world experience in the rapidly advancing cell & gene therapy field and working with cutting-edge gene-editing technology such as CRISPR, come join us! This role in the Large-Scale Platform Team will support the development and optimization of multiple unit operations in allogeneic chimeric antigen receptor T (CAR-T) cell manufacturing platforms, and participate in the evaluation of novel technologies. You will be working under the supervision of a Process Development Engineer III, and collaborating with other research associates and teams across Intellia, including different Technical Operation units and research departments. Key responsibilities/learning opportunities for this role include:

• Assist or perform large-scale T-cell enrichment from healthy donor apheresis

• Media and buffer preparation

• T-cell culture in multiple culture systems

• Support cell washing and harvest operations

• Assist in data generation to support cell processing evaluations and fill-finish operations

• Characterize T-cells with flow cytometry and other basic immunology assays

• Support medium to large-scale process development runs

• Document experiments in an electronic lab notebook (ELN) in a timely manner

• Compile experiment data, communicate results, and formulate a hypothesis to a diverse group audience

• Assist in maintaining lab reagent and consumables inventory

About You:

The ideal candidate will have a high level of scientific curiosity and integrity, and will be ready to tackle a diverse set of responsibilities in a team setting where collaboration, delivery, accuracy, and quality are valued. You should be highly motivated and passionate to work in a fast-paced and growing environment and be a team player with an eye for continuous improvement. Additional role requirements include:

• Currently enrolled in a Bachelor’s degree in Biological Sciences, Biochemistry, Biotechnology, Bioengineering, Immunology, and Pharmaceutical Sciences or a closely related field

• Familiar with immunology and concepts concerning T-cell function and differentiation

• Ability to perform basic statistical analysis like T-test, ANOVA, etc.

• Strong verbal and written communication skills

• Ability to communicate effectively and thrive in a team with time-critical objectives

This role is open to students available to work 35-40h per week for 20-24 weeks, starting June/July - December 2023.

Meet your future team:

You will be mentored by a Process Development Engineer III in the Large-Scale Platform Team and work closely with other Associate Scientists, Process Engineers, and Research Associates. The Cell Therapy Process Development team is a group of fifteen motivated scientists and engineers that has three sub-teams with different focuses. We work in collaboration with our colleagues in research, analytical development, and other process development groups. We meet regularly to discuss data and share scientific discoveries and literature. In our group discussions, everyone is encouraged to ask questions and share their insights into the process. We strive to live the Intellia core values: thrive as ONE, EXPLORE what genomic medicine and cell therapy can do to change cancer patients’ lives around the world, challenge the status quo to DISRUPT, and DELIVER the best products we can bring to patients.

Covid-19 Vaccination Policy: All Intellia employees, regardless of work location, must be fully vaccinated for COVID-19. This requirement includes a booster dose once eligible. Requests for exemption for medical or sincerely held religious beliefs will be considered.

EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.