Senior PPK/PD Kineticist

We are looking for a Senior Pharmacokineticist who will support Pharmacokinetic (PK) and Pharmacodynamic (PD) requirements for Discovery and IND-stage project teams. This person will be providing input into / designing / coordinating early preclinical and nonclinical in vivo studies. Additionally, we expect the person in this role to be collaborating with Therapeutic Area scientific staff and/or CROs performing these studies.

A day in the life of the Sr PPK/PD Kineticist may look like:

• Serve on Discovery-stage project teams as a subject matter authority for the Preclinical Pharmacokinetics / Pharmacodynamics (PPK/PD) group, providing input to the design of preclinical PK/pharmacology studies.
• Collaborate effectively with various groups within Regeneron, to develop a PK strategy for each project and then deliver the required output.
• Optimally communicate project team queries, requests and expectations (i.e. timing and results) from the Project Teams to management.
• Conduct and report PK and PK/PD analyses using data derived from preclinical studies.

This may be the role for you if you:

• Enjoy preparing and presenting the PK/PD analyses to internal project teams and senior management, and writing summary reports and documents to support regulatory filings.
• Want to work in close association with the Toxicology, Pathology, Clinical Pharmacology and Quantitative Pharmacology (modeling & simulation) functions, within the Drug Safety and Pharmacometrics Department, to deliver data and study reports / regulatory documents in support of project progression.

In order to be considered qualified for this role you must:

Have a minimum of a PhD in Pharmacology, Pharmacokinetics, Biology/Molecular Biology, or Biochemistry, with at least 5 years of relevant industry experience (Biotech or Pharma). This experience should include:

In-depth theoretical and applied understanding of PK and PD, used to describe and understand the pharmacology/biology of therapeutic proteins (required)

Proven ability to plan, organize, lead all aspects of PK and/or PK/PD studies, and analyze PK/PD data (required)

Knowledge of and experience with relevant PK/PD software applications (e.g., WinNonLin) (preferred)

Experience in drafting PK reports and relevant IND sections (preferred)

Previous experience with protein/monoclonal antibody therapeutics in one or more of the following therapeutic areas - oncology, inflammation / immunology, metabolism, infectious disease or ophthalmology - (required)

Additional experience with other modalities, including siRNA, gene therapy, CAR-T and other modalities (preferred)

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits including health and wellness programs, fitness centers and equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.

The salary ranges provided are shown in accordance with U.S. law and apply to U.S. based positions, where the hired candidate will be located in the U.S. If you are outside the U.S, please speak with your recruiter about salaries and benefits in your location.

Salary Range (annually)

$121,200.00 - $197,800.00