Sr. Associate Scientist, Formulation Development (AAV, Gene Therapy)

Regeneron's Formulation Development Group (FDG) is seeking a highly motivated Sr. Associate Scientist as we work to support all stages of pre-clinical, clinical and commercial formulation and drug product development for Regeneron's Genetic Medicine.

We apply biochemical, biophysical and bioanalytical methods to carry out characterization and development studies primarily on viral vector-based gene therapy to support formulation and drug product development. In addition, we also support the development of antibody-based programs and will conduct research in collaborations with colleagues in Research and Preclinical Development to develop new technologies and platforms.

A Typical Day Might Look Like:

• Design and implement formulation development, characterization, and stability studies to support formulation and drug product development for viral vector-based gene therapy (e.g. AAV) and antibody programs.
• Develop phase-appropriate biochemical and biophysical methods as well as high-throughput biophysical methods for characterization of stability and degradation mechanisms of candidate molecules and drug products.
• Perform sample analysis supporting FDG activities
• Author technical documents, such as formulation development technical reports, to support the process development, manufacturing and regulatory filings.
• Apply statistical science knowledge for study design and data analysis.
• Present work at group, department, and cross-functional meetings.

This Role Might Be for You If:

• Good understanding of protein chemistry, biophysical/biochemical characterization of proteins, analytical method development, structure biology, and biomolecule product development is desirable.
• Knowledge or prior experience working with viral vectors, such as AAV, Lentivirus or cell therapy products is a plus.
• Hands-on experience with biochemical and biophysical techniques for protein characterization such as chromatography (SEC, IEX, RP), viscosity, gel electrophoresis (CE-SDS, MCE, cIEF, iCE), particle size (DLS, HIAC, MFI), spectroscopy (UV-Vis, CD, AUC, fluorescence), and thermostability characterization (DSC, DSF) is desirable.
• Ability to prioritize and lead multiple tasks.
• Thorough, self-motivated, effective team member with, good oral and written communication skills.

To be considered, you must have a BS degree with 5+ years or MS degree with 2+ years relevant laboratory experience. Degrees in Pharmaceutical Sciences, Biochemistry, Biophysics, Molecular Biology, Chemistry, Biomedical Engineering, or a related field are desirable. Relevant industry experience is preferred.

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Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits including health and wellness programs, fitness centers and equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.

The salary ranges provided are shown in accordance with U.S. law and apply to U.S. based positions, where the hired candidate will be located in the U.S. If you are outside the U.S, please speak with your recruiter about salaries and benefits in your location.

Salary Range (annually)

$75,700.00 - $123,500.00