Skip to main content

This job has expired

You will need to login before you can apply for a job.

Senior Scientist, Molecular Assays

Employer
Fate Therapeutics
Location
San Diego, CA
Start date
Dec 1, 2022

View more

Discipline
Science/R&D, Biotechnology
Required Education
Doctorate/PHD/MD
Position Type
Full time
Hotbed
Biotech Beach, Best Places to Work

Job Details

Fate Therapeutics is seeking a talented and highly motivated scientific leader with strong molecular biology skills to join a multidisciplinary team dedicated to discovery and productization of novel off-the-shelf cell-based immunotherapies. The primary function of this role will be managing and developing a core team dedicated to providing molecular biology support for the generation of engineered induced pluripotent stem cell (iPSC) master cell banks (MCBs). Main responsibilities include screening and characterization of engineered iPSC clones using quality-controlled SOPs and manufacturing and testing of plasmids using batch record.  The ideal candidate will have extensive experience with probe-based qPCR and ddPCR and a strong background of molecular biology and genetics. This position will require strong abilities to manage multiple projects and employees with aggressive timelines, and the ability to communicate effectively across multidisciplinary teams. This is a full-time position that reports to a Principal Scientist in the Molecular Engineering group and is located at the Company’s corporate headquarters in San Diego, California. 
Responsibilities
  • Lead a team to provide core molecular biology support to iPSC MCB generation
  • Support process development and manufacturing runs of MCB generation by screening, characterization, and release testing using molecular biology assays including conventional PCR, qPCR, ddPCR and sequencing
  • Design, optimize, and validate assays and establish quality-controlled SOPs
  • Coordinate with QA/Facilities/Manufacturing to establish controlled lab and protocols for GMP production of plasmids
  • Manage multiple projects by communicating with cross-functional teams, setting priorities and timelines, and ensuring timely delivery of high-quality results
  • Author research reports and contribute to IND filing
  • Communicate research and development findings in cross-disciplinary team meetings as well as with external partners

Qualifications
  • Ph.D. in molecular biology or related discipline with 7+ years of relevant experience in industry.
  • Expertise in design, optimization, qualification, and troubleshooting of conventional PCR, qPCR, ddPCR assays.
  • Clear understanding of standard methodology in analysis of outcome of genetic engineering.
  • Comfortable in a fast-paced environment and able to adjust workload based upon changing priorities.
  • Experience working with cGMP compliant/quality-controlled procedures.
  • Proven track record of managing multiple projects and managing and developing personnel.
  • Excellent communication and presentation skills.
  • Demonstrated success working in a cross-functional team environment.

Working Conditions and Physical Requirements
  • Will require working with blood and cell lines of human and animal origin
  • Will require working with hazardous materials
  • 100% on-site work at corporate headquarters in San Diego, CA
  • Occasional evening and weekend work will be required

The preceding job description indicates the general nature and level of work performed by employees within this classification. Additional and incidental duties related to the primary duties may be required from time to time.

Equal Employment Opportuntiy
Fate Therapeutics, Inc. is an equal opportunity employer. We value diversity and are committed to creating an inclusive environment for all employees.

Privacy Notice
You can view our online Privacy Notice here.

About Fate Therapeutics, Inc.
Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to the development of first-in-class cellular immunotherapies for patients with cancer. The Company has established a leadership position in the clinical development and manufacture of universal, off-the-shelf cell products using its proprietary induced pluripotent stem cell (iPSC) product platform. The Company’s immuno-oncology pipeline includes off-the-shelf, iPSC-derived natural killer (NK) cell and T-cell product candidates, which are designed to synergize with well-established cancer therapies, including immune checkpoint inhibitors and monoclonal antibodies, and to target tumor-associated antigens using chimeric antigen receptors (CARs). Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit www.fatetherapeutics.com.


Company

Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients with cancer and autoimmune disorders. Using its proprietary iPSC product platform, the Company has established a leadership position in creating multiplexed-engineered iPSC lines and in the manufacture and clinical development of off-the-shelf, iPSC-derived cell products. The Company’s effector cell pipeline includes multiplexed-engineered, iPSC-derived natural killer (NK) cell and T-cell product candidates, which incorporate novel synthetic controls of cell function, such as chimeric antigen receptors (CARs) to target tumor-associated antigens and are intended to deliver multiple mechanisms of therapeutic importance to patients including in combination with well-established cancer therapies. Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit www.fatetherapeutics.com.

Company info
Website
Phone
858.875.1800
Location
12278 Scripps Summit Drive
San Diego
California
92131
United States

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert