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Associate Scientist, Bioanalytical Development

Employer
Pionyr Immunotherapeutics
Location
South San Francisco, CA
Start date
Nov 29, 2022

View more

Discipline
Science/R&D, Biotechnology
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Bay
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Job Details

Pionyr Immunotherapeutics is a growing South San Francisco-based immuno-oncology company focused on novel approaches to generate anti-tumor immunity. Pionyr is looking for a highly motivated and dedicated candidate for a full-time Associate Scientist/Scientist position in our Preclinical Science group. The candidate will have an opportunity to play an integral role in advancing our therapeutic candidates into the clinic and supporting target discovery efforts.

The ideal candidate will have extensive experience in bioanalytical method development and will be responsible for designing and performing pharmacokinetics (PK), immunogenicity (ADA) and target engagement assays for large molecule therapeutics. You will have the opportunity to contribute to our programs from target validation to IND filing to clinical development.

Specific Responsibilities Include (but not limited to):

  • Develop validation-ready PK and immunogenicity assays to support preclinical and clinical studies.
  • Develop and optimize biomarker and target engagement assays for preclinical studies.
  • Collaborate closely with project teams to progress discovery projects.
  • Document method development and prepare technical reports.
  • Assist in communicating and interacting with contract research organizations (CRO)s.
  • Multi-task and deliver results under defined timelines.
  • Analyze data and present scientific results at appropriate meetings.


Requirements:

  • M.S. with 5+ years of experience, or B.S. with 10 + years of experience.
  • Hands-on experience in developing PK and ADA assays on Meso Scale Discovery (MSD) is essential.
  • Direct experience with quantitative immunoassay protocols, reagent QC and assay development is required.
  • Experience in bioanalytical method development and validation in accordance with regulatory guidelines is preferred.
  • Experience with flow cytometry, GyroLab, Quanterix, tissue culture, and automated liquid handling is a plus.
  • Experience with neutralizing antibody assay development for immunogenicity is a plus
  • Experience in assay transfer to CROs is desired.
  • Strong communication, presentation and teamwork skills as well as ability to collaboratively contribute to multiple projects in a fast-paced environment.
How to Apply

Pionyr Immunotherapeutics Inc. offers competitive salaries, participation in company stock-incentive plans and benefits packages, in addition to a dynamic academic-driven science environment. If you would like to be part of a team-based and collaborative company developing innovative immuno-oncology therapeutics, please send your resume.

Thank you for your interest in Pionyr Immunotherapeutics. We are an equal opportunity employer.

Company

Pionyr Immunotherapeutics is a clinical stage company developing cancer immunotherapies that target the tumor microenvironment to enhance the body’s antitumor immunity. The company’s approach, Myeloid Tuning™, is designed to enhance the immune system’s anti-tumor response by altering, or “tuning”, the myeloid infiltrate of the tumor microenvironment with high specificity and for very specific purposes.

The company was founded in 2015 by Max Krummel, Ph.D., a professor at University of California, San Francisco School of Medicine (UCSF), who has been making significant strides in immuno-oncology since the mid-1990s. Dr. Krummel is the co-inventor of YERVOY® (ipilimumab), the first checkpoint inhibitor, which was approved in 2011 to treat melanoma. Pionyr has exclusively licensed technology from UCSF based on Dr. Krummel’s work.

Our employees are passionate about Pionyr’s mission: To develop innovative therapeutics that dramatically alter the tumor microenvironment thereby enabling the human immune system to successfully fight and, potentially, eliminate cancer. We offer an environment where individuals make a difference and have a voice. At Pionyr, communication is open and transparent, teams are empowered, and quality and integrity are paramount.

We greatly value our employees, and this is reflected in the comprehensive and above market compensation and benefits packages we provide to support the health and well-being of our “Pionyrs” and their families.

Join us and become an integral part of a leading immune-oncology company where you will have a direct impact on our research and clinical programs and have an opportunity to learn from proven, experienced scientific and business leaders. We look forward to hearing from you.

Find Us
Website
Phone
(650) 825-6140
Location
2 Tower Pl, Suite 800
South San Francisco
CA
94080
US
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