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Research Scientist - Discovery Sciences and Technologies

Employer
Gilead Sciences, Inc.
Location
Foster City, CA
Start date
Nov 29, 2022

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Job Details

Research Scientist - Discovery Sciences and Technologies
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company’s five core values. That’s because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

Job Description


We are seeking a highly motivated and creative Research Scientist to join the Discovery Sciences and Technologies (DST) Department and contribute to our biochemistry capabilities to enable the identification and nomination of small molecule and biologics drug candidates across all therapeutic areas at Gilead.

DST Department members are responsible for the design and execution of rigorous, quantitative, and physiologically-relevant in vitro biochemical and functional cellular assays. They collaborate within multi-disciplinary teams to discover and evolve drug candidates from lead identification efforts during project inception to the characterization of the final development candidate.

The successful candidate will be an integral member of the DST research team and work closely with various Research functions such as medicinal chemistry, structural biology and protein therapeutics to advance transformational therapies into clinical development for patients. Gilead is a highly matrixed organization and the ability to work effectively across diverse functional groups and therapeutic areas is a key attribute for this role.

Specific Responsibilities:
  • Development of robust biophysical, enzymatic, and cellular assays to measure small molecule and biologics potency as well as functional activity.
  • Apply diverse methods and approaches (e.g. SPR, TR-FRET, AlphaLISA, quantitative cellular and biochemical assays) to elucidate mechanisms of inhibitor action on target proteins and cellular signaling pathways.
  • Perform critical experiments to enable hit identification (HTS, DEL, FBDD, immunization, phage display), hit-to-lead and lead optimization across therapeutic modalities.
  • Provide scientific insight and in-depth data interpretation to inform decision making at the project team and leadership levels.
  • Evaluate and implement new technologies to support advancement of internal programs and core group functions.
  • May involve mentoring associates, providing scientific direction and guidance.
  • Contribute to several projects at any given time, work successfully in a cross-functional team environment and communicate clearly both verbally and in writing to a variety of audiences.


Minimum Qualifications:

  • PhD in biochemistry or a related scientific discipline and direct experience in assay development and/or inhibitor mechanism of action studies. Post-doctoral experience in an academic or industry setting preferred.
  • Strong technical background in biophysics (biosensors or other methods to characterize molecular interactions) or enzymology.
  • Experience with cell culture and cellular assays would be desirable.
  • The candidate should be able to think critically and creatively across multiple disciplines and have demonstrated the ability to solve research problems using in vitro assays, including assay optimization, and troubleshooting. Must be detail orientated and organized.
  • Strong interpersonal and communication skills, with enthusiasm for working in an environment characterized by rigorous scientific and innovative thinking.
  • Excellent written and oral organizational skills.
  • 0 to 2 years of experience

For jobs in the United States:


As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@gilead.com for assistance.

Following extensive monitoring, research, consideration of business implications and advice from internal and external experts, Gilead has made the decision to require all U.S., Canada, Australia, Singapore, and Hong Kong employees and contractors to receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.​

For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.

NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT

PAY TRANSPARENCY NONDISCRIMINATION PROVISION

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:


Please log onto your Internal Career Site to apply for this job.






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Company

Gilead Sciences is a biopharmaceutical company that discovers, develops, and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide. Headquartered in Foster City, California, Gilead has operations in North America, Europe and Australia.
 

Find Us
Website
Location
333 Lakeside Drive
Foster City
California
94404
United States
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