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Post Doc Scientist, Oncology, Tumor Microenvironment (TME)

Employer
Gilead Sciences, Inc.
Location
Foster City, CA
Start date
Nov 27, 2022

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Discipline
Science/R&D, Biotechnology, Oncology
Required Education
Doctorate/PHD/MD
Position Type
Full time
Hotbed
Biotech Bay, Best Places to Work
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Job Details

Post Doc Scientist, Oncology, Tumor Microenvironment (TME)
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company’s five core values. That’s because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

Job Description


About Gilead:

Gilead is a research-based biopharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. We are actively seeking candidates for the inaugural class of our new Postdoctoral Scholar Program in Gilead Research. This is an opportunity to conduct cutting-edge independent research at a highly innovative company. We welcome all qualified candidates to apply!

Summary:

The Postdoctoral position in the laboratory of Jamie Bates provides a unique opportunity for independent research investigating novel approaches to relieve immunosuppression imposed by the tumor microenvironment (TME). Cancer associated fibroblasts and myeloid cells, endothelial cells, and the extracellular matrix can provide suppressive signals that prevent T cell activation, and/or promote T cell exclusion.

The successful candidate will be expected to design an independent research program aimed at delineating key drivers of TME-driven immunosuppression with the goal of providing rationale for a novel combination partner for immunotherapy. The candidate will be invited to take advantage of cutting-edge technologies available at Gilead such as spectral flow cytometry analysis, single-cell RNAseq and spatial transcriptomics, while collaborating with multiple groups with expertise in recombinant protein generation, cell based assay optimization, immunostaining and multiplexing with quantitative analysis, in vivo pharmacology, as well as state-of-the art bioinformatics capabilities.

The results of these studies will inform the rational design of novel therapeutics intended to broaden the number of patients who respond to immunotherapy by providing TME-targeting approaches that can overcome innate and adaptive mechanisms of resistance. The fellow will be encouraged to design their own research plan, publish their work in top tier journals, and present at scientific conferences.

The selected candidate will work in a highly collaborative environment at Gilead, with an emphasis on high impact publications. This postdoctoral position provides access to world class research facilities and the opportunity to leverage expertise and resources across multiple functional areas at Gilead Sciences Inc.

Minimum Qualifications:

Candidates should have a Ph.D. in Molecular Biology, Cell Biology, Immunology or related field, a record of independent high impact research as evidenced by publications and experience in one or more of the following areas:
  • Inflammation/Oncology
  • Stromal or myeloid biology
  • TGF-β presentation and/or signaling mechanisms
  • In-vitro and/or in-vivo study of immune cell biology


Keywords: Post Doc Fellow, Post Doc Fellowship, Post Doctoral Fellow, Post Doctoral Fellowship, Post Doctorate, Postdoc, Post Doctoral Scientist

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As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@gilead.com for assistance.

Following extensive monitoring, research, consideration of business implications and advice from internal and external experts, Gilead has made the decision to require all U.S., Canada, Australia, Singapore, and Hong Kong employees and contractors to receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.​

For more information about equal employment opportunity protections, please view the 'EEO is the Law' poster.

NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT

PAY TRANSPARENCY NONDISCRIMINATION PROVISION

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:


Please log onto your Internal Career Site to apply for this job.






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Company

Gilead Sciences is a biopharmaceutical company that discovers, develops, and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide. Headquartered in Foster City, California, Gilead has operations in North America, Europe and Australia.
 

Find Us
Website
Location
333 Lakeside Drive
Foster City
California
94404
US
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