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Sr. Research Associate I, Cell Biology

AnaptysBio, Inc.
San Diego, CA
Start date
Nov 27, 2022

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Job Details

Job Type Full-time

Position Summary

The Sr. Research Associate I will independently plan, design, execute, and analyze experiments, with supervisor review, to meet project team goals. This role will require review and incorporation of theoretical and technical aspects of experimental methods from relevant scientific literature. This role will also require the ability to think critically, understanding of data analysis and presentation, and communication of experimental findings in both individual and team settings. 

Essential Functions

  • Isolation of PBMCs and/or immune cell subtypes from human and NHP whole blood 
  • Coordination and maintenance of annual CRO contracts for blood donation programs 
  • Experience with sterile technique and mammalian cell culture, including both established cell lines and primary immune cells
  • Knowledge of functional assays for both T and B cells 
  • Development of cell-based assays, including, but not limited to: cell proliferation, cell signaling, and cytokine production
  • Expertise with flow cytometry, including analysis of ligand/receptor binding, receptor quantification, and intracellular cytokine detection
  • Experience with cytokine analysis by ELISA, luminex, and MSD
  • Familiarity with analysis of scientific datasets, including GraphPad PRISM
  • Presentation of experimental results at project and department meetings
  • Mentorship of more junior associates to troubleshoot their experiments


Education & Experience: 

  • BA/BS or equivalent in a related scientific discipline and a minimum of 5 years relevant experience

Physical Demands

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this job, the employee is regularly required to sit and talk or hear. The employee frequently is required to use hands to finger, handle, or feel. The employee is occasionally required to stand, walk, and reach with hands and arms. The employee must occasionally lift and/or move up to 10 pounds. Specific vision abilities required by this job include close vision and ability to adjust focus in order to read.

Work Environment

The work environment characteristics are representative of those an employee encounters while performing the essential functions of this job, typically in an open office environment. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

The noise level in the work environment is usually moderate.

This position requires working with biological and/or chemical hazards.

All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status. 


AnaptysBio is a clinical-stage biotechnology company focused on delivering innovative immunology therapeutics. We are developing immune cell modulators, including two checkpoint agonists in clinical-stage development, for autoimmune and inflammatory disease: rosnilimab, our anti-PD-1 agonist program in Phase 2 for the treatment of moderate-to-severe alopecia areata; and ANB032, our anti-BTLA agonist program. AnaptysBio is also developing imsidolimab, our anti-IL-36R antibody in Phase 3 for the treatment of generalized pustular psoriasis, or GPP. We also have additional preclinical programs and discovery research of potentially innovative immunology therapeutics, including ANB033, an anti-CD122 antagonist antibody for the treatment of inflammatory diseases. AnaptysBio has also developed multiple therapeutic antibodies in an immuno-oncology collaboration with GSK, including an anti-PD-1 antagonist antibody (JEMPERLI (dostarlimab-gxly)), an anti-TIM-3 antagonist antibody (cobolimab, GSK4069889) and an anti-LAG-3 antagonist antibody (GSK4074386).

Find Us
10770 Wateridge Circle
Suite 210
San Diego
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