Research Associate (Assay Development)

The Role: BigHat Biosciences is seeking a self-motivated individual for a Research Associate or Associate Scientist role* to contribute to and support research on multiple therapeutic optimization projects.
*At BigHat we believe in titles that are commensurate with skill set, relative organizational impact, and value contribution; more experienced candidates are encouraged to apply, with the understanding that responsibilities and title would adjust as appropriate. 
Key Responsibilities

• Planning and execution of experiments to optimize antibody expression, stability, activity, and binding affinity.
• Maintain cell cultures and assess activity of therapeutic antibody candidates using in vitro cell-based functional assays.
• Contribute to the development and optimization of new assay types to be run at high throughput.
• Follow laboratory protocols, create SOPs, and keep a detailed record of all experiments using BigHat’s documentation tools.
• Summarize results and critical problems in writing and in presentation to a collaborative, cross-functional team.

About You Undergraduate or Master’s degree in the biological sciences; familiarity with protein biochemistry; lab experience with Western Blot or SDS-PAGE; strongly self-motivated individual with attention to detail; driven, team-oriented, and excited to work in a dynamic startup environment. 

Nice to Haves:

• Bachelor’s degree in immunology, genetics, or biochemistry
• Hands-on knowledge of protein expression and purification
• Prior experience with cloning and mammalian cell culture
• Experience with ELISA/immunoassay and BLI/SPR
• Familiarity (or interest in) operating automated liquid handlers
• Ability to manipulate and analyze data in R/Python