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Research Associate (Assay Development)

BigHat Biosciences
San Mateo, CA
Start date
Nov 19, 2022

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Regulatory, Research/Documentation, Science/R&D, Research
Required Education
Bachelors Degree
Position Type
Full time
Biotech Bay
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The Role: BigHat Biosciences is seeking a self-motivated individual for a Research Associate or Associate Scientist role* to contribute to and support research on multiple therapeutic optimization projects.
*At BigHat we believe in titles that are commensurate with skill set, relative organizational impact, and value contribution; more experienced candidates are encouraged to apply, with the understanding that responsibilities and title would adjust as appropriate. 
Key Responsibilities
  • Planning and execution of experiments to optimize antibody expression, stability, activity, and binding affinity.
  • Maintain cell cultures and assess activity of therapeutic antibody candidates using in vitro cell-based functional assays.
  • Contribute to the development and optimization of new assay types to be run at high throughput.
  • Follow laboratory protocols, create SOPs, and keep a detailed record of all experiments using BigHat’s documentation tools.
  • Summarize results and critical problems in writing and in presentation to a collaborative, cross-functional team.

About You Undergraduate or Master’s degree in the biological sciences; familiarity with protein biochemistry; lab experience with Western Blot or SDS-PAGE; strongly self-motivated individual with attention to detail; driven, team-oriented, and excited to work in a dynamic startup environment. 

Nice to Haves:
  • Bachelor’s degree in immunology, genetics, or biochemistry
  • Hands-on knowledge of protein expression and purification
  • Prior experience with cloning and mammalian cell culture
  • Experience with ELISA/immunoassay and BLI/SPR
  • Familiarity (or interest in) operating automated liquid handlers
  • Ability to manipulate and analyze data in R/Python
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