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Research Technologist / Senior Research Technologist, Genomics Core

Gladstone Institutes
San Francisco, CA
Start date
Nov 8, 2022

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Regulatory, Science/R&D, Research, Genomics
Required Education
Bachelors Degree
Position Type
Full time
Biotech Bay
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Job Details

Lab/Area:Genomics Core


The Genomics Core provides state-of-the-art genomic and next generation sequencing (NGS) services to support basic and translational research for academic institutions and industry sectors.

We are currently recruiting for a highly motivated molecular biologist to join our Genomics Core Laboratory as a Research Technologist / Senior Research Technologist. This is a laboratory-based position, and expertise in NGS techniques is highly preferred. The successful candidate will work independently and as part of a team on single cell and spatial genomics projects employing various NGS-based methods and emerging technologies. In this role, the candidate will work in a highly interactive environment while maintaining a high degree of autonomy. The candidate is expected to become a central member of the lab, participating in consultation, planning and executing experiments, contributing to data interpretation, and communicating results to team and customers.

The Genomics Core loves to invest in developing our scientists. We offer opportunities for learning and growing professionally. Candidates who are highly skilled at molecular biology techniques, would like to pursue a career in the fields of genomics and NGS, and enjoy interacting with researchers from different areas of research are encouraged to apply.


  • Independently run, optimize and troubleshoot existing NGS library preparation pipelines including, but not limited to, single cell and spatial genomics and bulk RNA/DNA-seq

  • Develop and optimize custom NGS-based assays and emerging genomic technologies under manager supervision

  • Assess cell/nuclei/nucleic acid quality at checkpoints throughout NGS library preparation – from incoming sample quality control (QC) to final library validation

  • Isolation of nucleic acids from frozen cells/tissues and FFPE tissue sections

  • Ensure scientific rigor and be highly committed to deliver high quality results in a fast-paced and constantly evolving environment

  • Maintain accurate, timely and detailed records of work

  • Communicate results and issues with lab members and customers with clarity and precision, both verbally and in writing in a timely fashion

  • General lab maintenance including instrument maintenance and supply ordering


  • BS/MS in Molecular Biology, Biochemistry, Biomedical Engineering or related discipline with 1+ year of relevant laboratory experience

  • Understanding of NGS technologies and applications including sample preparation, library construction, sequencing, QC, and data interpretation

  • Hands-on experience with cell biological and molecular techniques including cell culture, nucleic acid isolation and nucleic acid QC and quantitation (Bioanalyzer, qPCR, etc.)

  • Hands-on experience with some of NGS techniques and platforms (RNA-seq, ATAC-seq, ChIP-seq, amplicon seq, 10x Genomics, Illumina NGS, PacBio, etc.) is a plus

  • Experience with operating 10x Chromium and Illumina sequencers and interpreting sequencing QC metrics is a plus but not required

  • Demonstrated ability to learn quickly and apply new concepts and skills

  • Highly analytical with problem-solving skills and high level of attention to detail

  • Strong verbal and written communication skills

  • Strong interpersonal skills and team ethic with a customer service approach

  • Capacity to handle multiple projects concurrently; set priorities, maintain flexibility and meet deadlines

Additional Information:
  • Title and salary will be commensurate with education and experience.
  • Be a part of big ideas and consider Gladstone. Your difference will make a difference in human health.
  • Gladstone is an equal opportunity employer.


Gladstone is an independent, nonprofit life science research organization located in the epicenter of biomedical and technological innovation in the San Francisco Bay Area. Gladstone has created a research model that disrupts how science is done, funds big ideas, and attracts the brightest minds. Gladstone Institutes leads the way for innovative research in the biomedical field. We always seek dedicated and talented individuals to join our team.

Scientists know that using a diversity of approaches is often the most efficient strategy for solving a problem. New and different perspectives engender the very innovation that Gladstone prizes. This is one of the many reasons why we value diversity at Gladstone—be that a diversity of race, culture, religion, mental or physical ability, heritage, age, gender, sexual orientation or other characteristics. Our employees hail from more than 30 countries around the globe and we seek to hire the best and brightest for our diverse team of scientists and administrators. Career opportunities are available in both our administrative offices and our research areas.

Our Benefits
Gladstone offers eligible employees—and their dependents—a comprehensive range of benefits, including health insurance, retirement savings, and professional development.


  • Health and Retirement
    • A choice of medical plans, flexible spending account, and retirement account options that include employer contributions help you take care of your health and your future.
  • Time Away from Work
    • More than just vacation days, our paid and unpaid leave policies offer flexibility to help you confront different stages of life including maternity and paternity leave, as well as other types of family leave.
  • Professional Development
    • Gladstone encourages employees to seek the skills they need to remain at the forefront of their profession. By supporting professional development workshops and continuing education, Gladstone provides employees with the resources they need to evolve in their role and in their career.
  • Gladstone Cares
    • A specially selected suite of benefits to support you in and out of the workplace. Includes resources for dealing with the many stages of life to specific coverage for family planning, and back-up child or elder care coverage.
Find Us
1650 Owens Street
San Francisco
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