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Health Economics & Outcomes Research (HEOR) Senior Manager (US Remote)

Los Angeles, CA
Start date
Sep 30, 2022
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Job Details


If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborators who achieve togetherresearching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. Its time for a career you can be proud of. Join us.

Health Economics & Outcomes Research (HEOR) Senior ManagerLive

What you will do

Lets do this. Lets change the world! Reporting to the HEOR Director, the HEOR Senior Manager is accountable for executing on the HEOR Book of Work, strategically aligned with the Access Strategy Lead (ASL), for one or several assets across the life cycle management

The HEOR Book of Work comprises generating global-impact payer-relevant evidence, patient reported outcomes (PRO) and clinical outcomes assessment (COA) strategy, and evidence synthesis. Additionally, the HEOR Senior Manager is responsible to ensure delivery of global core materials to support Health Technology Assessment (HTA) submissions, including the Global Value Dossier (GVD) and economic models

The HEOR Senior Manager role involves execution of deliverables, as well as engaging with internal and external stakeholders.


This role is global, with tactical execution. The HEOR Senior Manager will use their expertise in developing payer-relevant evidence generation, PRO/COA strategy, evidence synthesis and HTA requirements.

The HEOR Senior Manager needs to engage effectively with internal customers to align and support the comprehensive HEOR plan, including the ASL, top-10 countries and cross-functional teams: Evidence Generation Team (EGT), Global Medical Affairs Team (GMAT), Center for Observational Research, Real-world Evidence sub-Team (RWEsT), Global Biostatistical Sciences, US Value Marketing, Medical Value & Access.

HEOR Book of Work:

  • Payer-relevant evidence generation plan and execution of global-impact and United States local-impact studies.

  • PRO/COA strategy

  • Evidence synthesis

  • Global core materials supporting HTA requirements

The HEOR Senior Manager will also engage with vendors and external experts to validate HEOR strategy and technical approach.

The HEOR Senior Manager's main responsibilities include:

  • Translating strategic objectives into concrete execution via HEOR project plan

  • Maintaining strong working relationships with top-10 countries, particularly the United States

  • Ensuring compliance with HTA dossier governance

DAI framework:

  • D: Drives execution of the HEOR Book of Work

  • A: Advices on payer-relevant evidence and HTA strategy to ASL and Global Access Team (GAT)

  • I: Informed of Integrated Access Strategy (IAS) plans


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The technically astute professional we seek is a collaborative partner with these qualifications.

Basic Qualifications

Doctorate degree and 2 years of health economics & outcomes research experience


Master's degree and 6 years of health economics & outcomes research experience


Bachelor's degree and 8 years of health economics & outcomes research experience


Associates degree and 10 years ofhealth economics & outcomes research experience


High school diploma / GED and 12 years ofhealth economics & outcomes research experience

Preferred QualificationsHealth economics training (on the job or academic)Experience in writing research protocols and publicationsExperience in developing payer-relevant evidence, including real-world evidenceExperience in designing PRO/COA strategyExperience in evidence synthesis (systematic literature reviews, indirect treatment comparisons and meta-analyses)Strategic and technical understanding of HTA requirements Experience in developing GVDs and AMCP dossiersExperience in developing economic models andpredictive analyticsExperience in the United States marketExperience in influencing Access strategy with a HEOR lensExperience in Amgen products' specific therapeutic areasExperience with direct country HTA interactionsExperience in early HTA engagement Ability to work with customers and colleagues based in different time zonesGood presentation and communication skillsGood interpersonal and soft skillsAbility to influence without authorityUnderstanding of clinical development process and regulatory evidence needs Ability to synthesize complex technical terms for non-technical audience Strategic thinking, while focusing on tactical executionThrive

What you can expect of us

As we work to develop treatments that take care of others, so we work to care for our teammates professional and personal growth and well-being.

  • Vast opportunities to learn and move up and across our global organization

  • Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

  • Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits

Apply now

for a career that defies imagination

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.
Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen requires all staff in the United States, Puerto Rico and Canada to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.


We are all different, yet we have this in common: our mission to serve patients. This sense of shared purpose is key to our becoming one of the world’s leading biotechnology companies. It guides us as we continue to launch new medicines and reach millions of patients worldwide.

We live the mission.

We win together.

We thrive on continual challenge.

Our team of 22,000+ scientists and professionals worldwide bring distinct perspectives and experiences to all we do. We leverage our global talent to achieve together—to research, manufacture and deliver ever-better products and greater depth to our mission.

At Amgen, there is a strong correlation between our high level of diversity and performance. Because addressing issues with a wider range of perspectives and approaches leads to more creative problem-solving. Together, we’re transforming the promise of science and biotechnology into therapies that have the power to restore health.

Connect with us to explore how you can Win, Live, and Thrive at Amgen.


Find Us
Corporate Headquarters
One Amgen Center Drive
Thousand Oaks
United States
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